Miyaji Y - Search Results

1

Pharmacokinetics and disposition of recombinant human osteoprotegerin (rhOPG) after intravenous administration in female fischer rats.

Miyaji Y, Kurihara A, Kamiyama E, Shiiki T, Kawai K, Okazaki O. Miyaji Y, et al. Xenobiotica. 2009 Feb;39(2):113-24. doi: 10.1080/00498250802590745. Xenobiotica. 2009. PMID: 19255937

2

Distribution of KAI-9803, a novel δ-protein kinase C inhibitor, after intravenous administration to rats.

Miyaji Y, Walter S, Chen L, Kurihara A, Ishizuka T, Saito M, Kawai K, Okazaki O. Miyaji Y, et al. Drug Metab Dispos. 2011 Oct;39(10):1946-53. doi: 10.1124/dmd.111.040725. Epub 2011 Jun 28. Drug Metab Dispos. 2011. PMID: 21712433

3

Novel comb-shaped PEG modification enhances the osteoclastic inhibitory effect and bone delivery of osteoprotegerin after intravenous administration in ovariectomized rats.

Miyaji Y, Kasuya Y, Furuta Y, Kurihara A, Takahashi M, Ogawara K, Izumi T, Okazaki O, Higaki K. Miyaji Y, et al. Pharm Res. 2012 Nov;29(11):3143-55. doi: 10.1007/s11095-012-0807-4. Epub 2012 Jun 23. Pharm Res. 2012. PMID: 22729371

4

Use of an intravenous microdose of 14C-labeled drug and accelerator mass spectrometry to measure absolute oral bioavailability in dogs; cross-comparison of assay methods by accelerator mass spectrometry and liquid chromatography-tandem mass spectrometry.

Miyaji Y, Ishizuka T, Kawai K, Hamabe Y, Miyaoka T, Oh-hara T, Ikeda T, Kurihara A. Miyaji Y, et al. Drug Metab Pharmacokinet. 2009;24(2):130-8. doi: 10.2133/dmpk.24.130. Drug Metab Pharmacokinet. 2009. PMID: 19430168 Free article.

5

In vitro evaluation of the potential for drug-induced toxicity based on (35)S-labeled glutathione adduct formation and daily dose.

Miyaji Y, Makino C, Kurihara A, Suzuki W, Okazaki O. Miyaji Y, et al. Bioanalysis. 2012 Feb;4(3):263-9. doi: 10.4155/bio.11.316. Bioanalysis. 2012. PMID: 22303830

6

Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.

Nakayama S, Takakusa H, Watanabe A, Miyaji Y, Suzuki W, Sugiyama D, Shiosakai K, Honda K, Okudaira N, Izumi T, Okazaki O. Nakayama S, et al. Among authors: miyaji y. Drug Metab Dispos. 2011 Jul;39(7):1247-54. doi: 10.1124/dmd.111.039180. Epub 2011 Apr 5. Drug Metab Dispos. 2011. PMID: 21467212

7

Appearance of double peaks in plasma concentration-time profile after oral administration depends on gastric emptying profile and weight function.

Metsugi Y, Miyaji Y, Ogawara K, Higaki K, Kimura T. Metsugi Y, et al. Among authors: miyaji y. Pharm Res. 2008 Apr;25(4):886-95. doi: 10.1007/s11095-007-9469-z. Epub 2007 Oct 23. Pharm Res. 2008. PMID: 17955185

8

Advantage of the Dissolution/Permeation System for Estimating Oral Absorption of Drug Candidates in the Drug Discovery Stage.

Miyaji Y, Fujii Y, Takeyama S, Kawai Y, Kataoka M, Takahashi M, Yamashita S. Miyaji Y, et al. Mol Pharm. 2016 May 2;13(5):1564-74. doi: 10.1021/acs.molpharmaceut.6b00044. Epub 2016 Apr 13. Mol Pharm. 2016. PMID: 27031624

9

Dissolution testing of modified release products with biorelevant media: An OrBiTo ring study using the USP apparatus III and IV.

Reppas C, Vrettos NN, Dressman J, Andreas CJ, Miyaji Y, Brown J, Etherson K, Hanley S, Karkossa F, Karlsson E, Klein S, Maier GM, McAllister M, Mistry N, Rosenblatt K, Schäfer KJ, Smith KL, Tomaszewska I, Williams J, Winge F, Vertzoni M. Reppas C, et al. Among authors: miyaji y. Eur J Pharm Biopharm. 2020 Nov;156:40-49. doi: 10.1016/j.ejpb.2020.08.025. Epub 2020 Aug 31. Eur J Pharm Biopharm. 2020. PMID: 32882421

10

An in silico approach to determine challenges in the bioavailability of ciprofloxacin, a poorly soluble weak base with borderline solubility and permeability characteristics.

Hansmann S, Miyaji Y, Dressman J. Hansmann S, et al. Among authors: miyaji y. Eur J Pharm Biopharm. 2018 Jan;122:186-196. doi: 10.1016/j.ejpb.2017.10.019. Epub 2017 Oct 27. Eur J Pharm Biopharm. 2018. PMID: 29111469

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