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4-hydroxynonenal, a lipid peroxidation product of dietary polyunsaturated fatty acids, has anticarcinogenic properties in colon carcinoma cell lines through the inhibition of telomerase activity.
Pizzimenti S, Menegatti E, Berardi D, Toaldo C, Pettazzoni P, Minelli R, Giglioni B, Cerbone A, Dianzani MU, Ferretti C, Barrera G. Pizzimenti S, et al. Among authors: pettazzoni p. J Nutr Biochem. 2010 Sep;21(9):818-26. doi: 10.1016/j.jnutbio.2009.06.005. Epub 2009 Sep 3. J Nutr Biochem. 2010. PMID: 19733043
PPARgamma ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells.
Toaldo C, Pizzimenti S, Cerbone A, Pettazzoni P, Menegatti E, Daniela B, Minelli R, Giglioni B, Dianzani MU, Ferretti C, Barrera G. Toaldo C, et al. Among authors: pettazzoni p. J Cell Mol Med. 2010 Jun;14(6A):1347-57. doi: 10.1111/j.1582-4934.2009.00966.x. Epub 2009 Nov 13. J Cell Mol Med. 2010. PMID: 19912441 Free PMC article.
Exposure of HL-60 human leukaemic cells to 4-hydroxynonenal promotes the formation of adduct(s) with alpha-enolase devoid of plasminogen binding activity.
Gentile F, Pizzimenti S, Arcaro A, Pettazzoni P, Minelli R, D'Angelo D, Mamone G, Ferranti P, Toaldo C, Cetrangolo G, Formisano S, Dianzani MU, Uchida K, Dianzani C, Barrera G. Gentile F, et al. Among authors: pettazzoni p. Biochem J. 2009 Aug 13;422(2):285-94. doi: 10.1042/BJ20090564. Biochem J. 2009. PMID: 19508232
AS601245, an Anti-Inflammatory JNK Inhibitor, and Clofibrate Have a Synergistic Effect in Inducing Cell Responses and in Affecting the Gene Expression Profile in CaCo-2 Colon Cancer Cells.
Cerbone A, Toaldo C, Pizzimenti S, Pettazzoni P, Dianzani C, Minelli R, Ciamporcero E, Roma G, Dianzani MU, Canaparo R, Ferretti C, Barrera G. Cerbone A, et al. Among authors: pettazzoni p. PPAR Res. 2012;2012:269751. doi: 10.1155/2012/269751. Epub 2012 Feb 29. PPAR Res. 2012. PMID: 22619672 Free PMC article.
Interaction of aldehydes derived from lipid peroxidation and membrane proteins.
Pizzimenti S, Ciamporcero E, Daga M, Pettazzoni P, Arcaro A, Cetrangolo G, Minelli R, Dianzani C, Lepore A, Gentile F, Barrera G. Pizzimenti S, et al. Among authors: pettazzoni p. Front Physiol. 2013 Sep 4;4:242. doi: 10.3389/fphys.2013.00242. Front Physiol. 2013. PMID: 24027536 Free PMC article. Review.
60 results