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Discovery of 6-({4-[2-(4-tert-butylphenyl)-1H-benzimidazol-4-yl]piperazin-1-yl}methyl)quinoxaline (WAY-207024): an orally active antagonist of the gonadotropin releasing hormone receptor (GnRH-R).
Pelletier JC, Chengalvala MV, Cottom JE, Feingold IB, Green DM, Hauze DB, Huselton CA, Jetter JW, Kopf GS, Lundquist JT, Magolda RL, Mann CW, Mehlmann JF, Rogers JF, Shanno LK, Adams WR, Tio CO, Wrobel JE. Pelletier JC, et al. Among authors: adams wr. J Med Chem. 2009 Apr 9;52(7):2148-52. doi: 10.1021/jm801572m. J Med Chem. 2009. PMID: 19271735
Design, synthesis, and SAR of new pyrrole-oxindole progesterone receptor modulators leading to 5-(7-fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348).
Fensome A, Adams WR, Adams AL, Berrodin TJ, Cohen J, Huselton C, Illenberger A, Kern JC, Hudak VA, Marella MA, Melenski EG, McComas CC, Mugford CA, Slayden OD, Yudt M, Zhang Z, Zhang P, Zhu Y, Winneker RC, Wrobel JE. Fensome A, et al. Among authors: adams wr, adams al. J Med Chem. 2008 Mar 27;51(6):1861-73. doi: 10.1021/jm701080t. Epub 2008 Mar 5. J Med Chem. 2008. PMID: 18318463
Initial Safety of Total Talus Replacement Used to Treat Talar Avascular Necrosis.
Abar B, Kim MS, Adams SB, Adams WR, Amendola A, Easley ME, Ellington JK, Ford SE, Hanselman AE, Highlander P, Kwon JY, Miller CP, Nunley JA, Parker C, Parekh SG, Schweitzer KM, Shawen SB, Mann T, Kelly C. Abar B, et al. Among authors: adams wr. Foot Ankle Int. 2024 Nov;45(11):1258-1265. doi: 10.1177/10711007241278947. Epub 2024 Oct 27. Foot Ankle Int. 2024. PMID: 39462286
Recurrent activity within microcircuits of macaque dorsolateral prefrontal cortex tracks cognitive flexibility.
Nolan SO, Melugin PR, Erickson KR, Adams WR, Farahbakhsh ZZ, Mcgonigle CE, Kwon MH, Costa VD, Lapish CC, Hackett TA, Cuzon Carlson VC, Constantinidis C, Grant KA, Siciliano CA. Nolan SO, et al. Among authors: adams wr. bioRxiv [Preprint]. 2023 Sep 24:2023.09.23.559125. doi: 10.1101/2023.09.23.559125. bioRxiv. 2023. PMID: 38529503 Free PMC article. Preprint.
80 results