Oyer JA - Search Results

1

Aberrant epigenetic silencing is triggered by a transient reduction in gene expression.

Oyer JA, Chu A, Brar S, Turker MS. Oyer JA, et al. PLoS One. 2009;4(3):e4832. doi: 10.1371/journal.pone.0004832. Epub 2009 Mar 12. PLoS One. 2009. PMID: 19279688 Free PMC article.

2

Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation.

Oyer JA, Yates PA, Godsey S, Turker MS. Oyer JA, et al. Mutat Res. 2011 Jan 10;706(1-2):21-7. doi: 10.1016/j.mrfmmm.2010.10.006. Epub 2010 Oct 28. Mutat Res. 2011. PMID: 21035468 Free PMC article.

3

Polycomb- and REST-associated histone deacetylases are independent pathways toward a mature neuronal phenotype.

McGann JC, Oyer JA, Garg S, Yao H, Liu J, Feng X, Liao L, Yates JR 3rd, Mandel G. McGann JC, et al. Among authors: oyer ja. Elife. 2014 Sep 24;3:e04235. doi: 10.7554/eLife.04235. Elife. 2014. PMID: 25250711 Free PMC article.

4

Cardiovascular and systemic microvascular effects of anti-vascular endothelial growth factor therapy for cancer.

Belcik JT, Qi Y, Kaufmann BA, Xie A, Bullens S, Morgan TK, Bagby SP, Kolumam G, Kowalski J, Oyer JA, Bunting S, Lindner JR. Belcik JT, et al. Among authors: oyer ja. J Am Coll Cardiol. 2012 Aug 14;60(7):618-25. doi: 10.1016/j.jacc.2012.02.053. Epub 2012 Jun 13. J Am Coll Cardiol. 2012. PMID: 22703929 Free PMC article.

5

C-terminal domain small phosphatase 1 and MAP kinase reciprocally control REST stability and neuronal differentiation.

Nesti E, Corson GM, McCleskey M, Oyer JA, Mandel G. Nesti E, et al. Among authors: oyer ja. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):E3929-36. doi: 10.1073/pnas.1414770111. Epub 2014 Sep 2. Proc Natl Acad Sci U S A. 2014. PMID: 25197063 Free PMC article.

6

A Mutation in Histone H2B Represents a New Class of Oncogenic Driver.

Bennett RL, Bele A, Small EC, Will CM, Nabet B, Oyer JA, Huang X, Ghosh RP, Grzybowski AT, Yu T, Zhang Q, Riva A, Lele TP, Schatz GC, Kelleher NL, Ruthenburg AJ, Liphardt J, Licht JD. Bennett RL, et al. Among authors: oyer ja. Cancer Discov. 2019 Oct;9(10):1438-1451. doi: 10.1158/2159-8290.CD-19-0393. Epub 2019 Jul 23. Cancer Discov. 2019. PMID: 31337617 Free PMC article.

7

Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies.

Oyer JA, Huang X, Zheng Y, Shim J, Ezponda T, Carpenter Z, Allegretta M, Okot-Kotber CI, Patel JP, Melnick A, Levine RL, Ferrando A, Mackerell AD Jr, Kelleher NL, Licht JD, Popovic R. Oyer JA, et al. Leukemia. 2014 Jan;28(1):198-201. doi: 10.1038/leu.2013.204. Epub 2013 Jul 4. Leukemia. 2014. PMID: 23823660 Free PMC article. No abstract available.

8

An activating mutation of the NSD2 histone methyltransferase drives oncogenic reprogramming in acute lymphocytic leukemia.

Swaroop A, Oyer JA, Will CM, Huang X, Yu W, Troche C, Bulic M, Durham BH, Wen QJ, Crispino JD, MacKerell AD Jr, Bennett RL, Kelleher NL, Licht JD. Swaroop A, et al. Among authors: oyer ja. Oncogene. 2019 Jan;38(5):671-686. doi: 10.1038/s41388-018-0474-y. Epub 2018 Aug 31. Oncogene. 2019. PMID: 30171259 Free PMC article.

9

UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition.

Ezponda T, Dupéré-Richer D, Will CM, Small EC, Varghese N, Patel T, Nabet B, Popovic R, Oyer J, Bulic M, Zheng Y, Huang X, Shah MY, Maji S, Riva A, Occhionorelli M, Tonon G, Kelleher N, Keats J, Licht JD. Ezponda T, et al. Cell Rep. 2017 Oct 17;21(3):628-640. doi: 10.1016/j.celrep.2017.09.078. Cell Rep. 2017. PMID: 29045832 Free PMC article.

10

PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by NSD2 Mutation in Pediatric Acute Lymphoblastic Leukemia.

Li J, Hlavka-Zhang J, Shrimp JH, Piper C, Dupéré-Richér D, Roth JS, Jing D, Casellas Román HL, Troche C, Swaroop A, Kulis M, Oyer JA, Will CM, Shen M, Riva A, Bennett RL, Ferrando AA, Hall MD, Lock RB, Licht JD. Li J, et al. Among authors: oyer ja. Cancer Discov. 2022 Jan;12(1):186-203. doi: 10.1158/2159-8290.CD-20-1771. Epub 2021 Aug 20. Cancer Discov. 2022. PMID: 34417224

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