Dynamics of KRas on endosomes: involvement of acidic phospholipids in its association.
Gelabert-Baldrich M, Soriano-Castell D, Calvo M, Lu A, Viña-Vilaseca A, Rentero C, Pol A, Grinstein S, Enrich C, Tebar F.
Gelabert-Baldrich M, et al. Among authors: lu a.
FASEB J. 2014 Jul;28(7):3023-37. doi: 10.1096/fj.13-241158. Epub 2014 Apr 9.
FASEB J. 2014.
PMID: 24719356
The endocytic compartment is emerging as a functional platform for controlling important cellular processes. We have found that 10 to 15% of total KRas, a protein that is frequently mutated in cancer, is present on endosomes, independent of its activation state. ... …
The endocytic compartment is emerging as a functional platform for controlling important cellular processes. We have found that 10 to …