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Substituted imidazopyridines as potent inhibitors of HCV replication.
Vliegen I, Paeshuyse J, De Burghgraeve T, Lehman LS, Paulson M, Shih IH, Mabery E, Boddeker N, De Clercq E, Reiser H, Oare D, Lee WA, Zhong W, Bondy S, Pürstinger G, Neyts J. Vliegen I, et al. J Hepatol. 2009 May;50(5):999-1009. doi: 10.1016/j.jhep.2008.12.028. Epub 2009 Feb 26. J Hepatol. 2009. PMID: 19303654 Free PMC article.
Selective inhibitors of picornavirus replication.
De Palma AM, Vliegen I, De Clercq E, Neyts J. De Palma AM, et al. Among authors: vliegen i. Med Res Rev. 2008 Nov;28(6):823-84. doi: 10.1002/med.20125. Med Res Rev. 2008. PMID: 18381747 Review.
Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors.
Paeshuyse J, Vliegen I, Coelmont L, Leyssen P, Tabarrini O, Herdewijn P, Mittendorfer H, Easmon J, Cecchetti V, Bartenschlager R, Puerstinger G, Neyts J. Paeshuyse J, et al. Among authors: vliegen i. Antimicrob Agents Chemother. 2008 Sep;52(9):3433-7. doi: 10.1128/AAC.01534-07. Epub 2008 Jul 14. Antimicrob Agents Chemother. 2008. PMID: 18625766 Free PMC article.
Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors.
Coelmont L, Kaptein S, Paeshuyse J, Vliegen I, Dumont JM, Vuagniaux G, Neyts J. Coelmont L, et al. Among authors: vliegen i. Antimicrob Agents Chemother. 2009 Mar;53(3):967-76. doi: 10.1128/AAC.00939-08. Epub 2008 Dec 22. Antimicrob Agents Chemother. 2009. PMID: 19104013 Free PMC article.
DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A.
Coelmont L, Hanoulle X, Chatterji U, Berger C, Snoeck J, Bobardt M, Lim P, Vliegen I, Paeshuyse J, Vuagniaux G, Vandamme AM, Bartenschlager R, Gallay P, Lippens G, Neyts J. Coelmont L, et al. Among authors: vliegen i. PLoS One. 2010 Oct 27;5(10):e13687. doi: 10.1371/journal.pone.0013687. PLoS One. 2010. PMID: 21060866 Free PMC article.
35 results