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Preclinical characterization of PF-00868554, a potent nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
Shi ST, Herlihy KJ, Graham JP, Nonomiya J, Rahavendran SV, Skor H, Irvine R, Binford S, Tatlock J, Li H, Gonzalez J, Linton A, Patick AK, Lewis C. Shi ST, et al. Among authors: patick ak. Antimicrob Agents Chemother. 2009 Jun;53(6):2544-52. doi: 10.1128/AAC.01599-08. Epub 2009 Mar 23. Antimicrob Agents Chemother. 2009. PMID: 19307358 Free PMC article.
In vitro antiviral activity and single-dose pharmacokinetics in humans of a novel, orally bioavailable inhibitor of human rhinovirus 3C protease.
Patick AK, Brothers MA, Maldonado F, Binford S, Maldonado O, Fuhrman S, Petersen A, Smith GJ 3rd, Zalman LS, Burns-Naas LA, Tran JQ. Patick AK, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2267-75. doi: 10.1128/AAC.49.6.2267-2275.2005. Antimicrob Agents Chemother. 2005. PMID: 15917520 Free PMC article. Clinical Trial.
In vitro resistance study of AG-021541, a novel nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
Shi ST, Herlihy KJ, Graham JP, Fuhrman SA, Doan C, Parge H, Hickey M, Gao J, Yu X, Chau F, Gonzalez J, Li H, Lewis C, Patick AK, Duggal R. Shi ST, et al. Among authors: patick ak. Antimicrob Agents Chemother. 2008 Feb;52(2):675-83. doi: 10.1128/AAC.00834-07. Epub 2007 Dec 10. Antimicrob Agents Chemother. 2008. PMID: 18070954 Free PMC article.
Identification and characterization of UK-201844, a novel inhibitor that interferes with human immunodeficiency virus type 1 gp160 processing.
Blair WS, Cao J, Jackson L, Jimenez J, Peng Q, Wu H, Isaacson J, Butler SL, Chu A, Graham J, Malfait AM, Tortorella M, Patick AK. Blair WS, et al. Among authors: patick ak. Antimicrob Agents Chemother. 2007 Oct;51(10):3554-61. doi: 10.1128/AAC.00643-07. Epub 2007 Jul 23. Antimicrob Agents Chemother. 2007. PMID: 17646410 Free PMC article.
In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease.
Patick AK, Binford SL, Brothers MA, Jackson RL, Ford CE, Diem MD, Maldonado F, Dragovich PS, Zhou R, Prins TJ, Fuhrman SA, Meador JW, Zalman LS, Matthews DA, Worland ST. Patick AK, et al. Antimicrob Agents Chemother. 1999 Oct;43(10):2444-50. doi: 10.1128/AAC.43.10.2444. Antimicrob Agents Chemother. 1999. PMID: 10508022 Free PMC article.
Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor.
Binford SL, Maldonado F, Brothers MA, Weady PT, Zalman LS, Meador JW 3rd, Matthews DA, Patick AK. Binford SL, et al. Among authors: patick ak. Antimicrob Agents Chemother. 2005 Feb;49(2):619-26. doi: 10.1128/AAC.49.2.619-626.2005. Antimicrob Agents Chemother. 2005. PMID: 15673742 Free PMC article.
74 results