Usha V - Search Results

1

Structure of the diaminopimelate epimerase DapF from Mycobacterium tuberculosis.

Usha V, Dover LG, Roper DI, Fütterer K, Besra GS. Usha V, et al. Acta Crystallogr D Biol Crystallogr. 2009 Apr;65(Pt 4):383-7. doi: 10.1107/S0907444909002522. Epub 2009 Mar 19. Acta Crystallogr D Biol Crystallogr. 2009. PMID: 19307721

2

Use of a codon alteration strategy in a novel approach to cloning the Mycobacterium tuberculosis diaminopimelic acid epimerase.

Usha V, Dover LG, Roper DL, Lloyd AJ, Besra GS. Usha V, et al. FEMS Microbiol Lett. 2006 Sep;262(1):39-47. doi: 10.1111/j.1574-6968.2006.00356.x. FEMS Microbiol Lett. 2006. PMID: 16907737

3

Characterization of Mycobacterium tuberculosis diaminopimelic acid epimerase: paired cysteine residues are crucial for racemization.

Usha V, Dover LG, Roper DL, Besra GS. Usha V, et al. FEMS Microbiol Lett. 2008 Mar;280(1):57-63. doi: 10.1111/j.1574-6968.2007.01049.x. FEMS Microbiol Lett. 2008. PMID: 18269631

4

Structure and function of Mycobacterium tuberculosis meso-diaminopimelic acid (DAP) biosynthetic enzymes.

Usha V, Lloyd AJ, Lovering AL, Besra GS. Usha V, et al. FEMS Microbiol Lett. 2012 May;330(1):10-6. doi: 10.1111/j.1574-6968.2012.02527.x. Epub 2012 Mar 7. FEMS Microbiol Lett. 2012. PMID: 22339732 Review.

5

Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase.

Usha V, Lloyd AJ, Roper DI, Dowson CG, Kozlov G, Gehring K, Chauhan S, Imam HT, Blindauer CA, Besra GS. Usha V, et al. Sci Rep. 2016 Mar 15;6:23191. doi: 10.1038/srep23191. Sci Rep. 2016. PMID: 26976706 Free PMC article.

6

Identification of novel diphenyl urea inhibitors of Mt-GuaB2 active against Mycobacterium tuberculosis.

Usha V, Gurcha SS, Lovering AL, Lloyd AJ, Papaemmanouil A, Reynolds RC, Besra GS. Usha V, et al. Microbiology (Reading). 2011 Jan;157(Pt 1):290-299. doi: 10.1099/mic.0.042549-0. Epub 2010 Nov 16. Microbiology (Reading). 2011. PMID: 21081761 Free article.

7

Synthesis of α-glucan in mycobacteria involves a hetero-octameric complex of trehalose synthase TreS and Maltokinase Pep2.

Roy R, Usha V, Kermani A, Scott DJ, Hyde EI, Besra GS, Alderwick LJ, Fütterer K. Roy R, et al. Among authors: usha v. ACS Chem Biol. 2013 Oct 18;8(10):2245-55. doi: 10.1021/cb400508k. Epub 2013 Aug 13. ACS Chem Biol. 2013. PMID: 23901909 Free PMC article.

8

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target.

Gurcha SS, Usha V, Cox JA, Fütterer K, Abrahams KA, Bhatt A, Alderwick LJ, Reynolds RC, Loman NJ, Nataraj V, Alemparte C, Barros D, Lloyd AJ, Ballell L, Hobrath JV, Besra GS. Gurcha SS, et al. Among authors: usha v. PLoS One. 2014 Nov 19;9(11):e113568. doi: 10.1371/journal.pone.0113568. eCollection 2014. PLoS One. 2014. PMID: 25409504 Free PMC article.

9

Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis.

Usha V, Hobrath JV, Gurcha SS, Reynolds RC, Besra GS. Usha V, et al. PLoS One. 2012;7(3):e33886. doi: 10.1371/journal.pone.0033886. Epub 2012 Mar 29. PLoS One. 2012. PMID: 22479467 Free PMC article.

10

Glycine and alanine dehydrogenase activities are catalyzed by the same protein in Mycobacterium smegmatis: upregulation of both activities under microaerophilic adaptation.

Usha V, Jayaraman R, Toro JC, Hoffner SE, Das KS. Usha V, et al. Can J Microbiol. 2002 Jan;48(1):7-13. doi: 10.1139/w01-126. Can J Microbiol. 2002. PMID: 11888165

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