Simpkins NS - Search Results

1

Concise enantioselective synthesis of ent-malbrancheamide B.

Frebault F, Simpkins NS, Fenwick A. Frebault F, et al. Among authors: simpkins ns. J Am Chem Soc. 2009 Apr 1;131(12):4214-5. doi: 10.1021/ja900688y. J Am Chem Soc. 2009. PMID: 19317498

2

Synthesis of the asperparaline core by a radical cascade.

Crick PJ, Simpkins NS, Highton A. Crick PJ, et al. Among authors: simpkins ns. Org Lett. 2011 Dec 16;13(24):6472-5. doi: 10.1021/ol202769f. Epub 2011 Nov 14. Org Lett. 2011. PMID: 22082317

3

Rapid access to polycyclic indolines related to the stephacidin alkaloids using a radical cascade.

Simpkins N, Pavlakos I, Male L. Simpkins N, et al. Chem Commun (Camb). 2012 Feb 14;48(14):1958-60. doi: 10.1039/c1cc16510k. Epub 2011 Dec 2. Chem Commun (Camb). 2012. PMID: 22134634

4

Enantioselective synthesis of cyclopropylcarboxamides using s-BuLi-sparteine-mediated metallation.

Lauru S, Simpkins NS, Gethin D, Wilson C. Lauru S, et al. Among authors: simpkins ns. Chem Commun (Camb). 2008 Nov 14;(42):5390-2. doi: 10.1039/b810441g. Epub 2008 Sep 16. Chem Commun (Camb). 2008. PMID: 18985220

5

The cascade radical cyclisation approach to prenylated alkaloids: synthesis of stephacidin A and notoamide B.

Simpkins NS, Pavlakos I, Weller MD, Male L. Simpkins NS, et al. Org Biomol Chem. 2013 Aug 14;11(30):4957-70. doi: 10.1039/c3ob40979a. Epub 2013 Jun 25. Org Biomol Chem. 2013. PMID: 23797367

6

A concise approach to a gelsemine core structure using an oxygen to carbon bridge swapping strategy.

Tchabanenko K, Simpkins NS, Male L. Tchabanenko K, et al. Among authors: simpkins ns. Org Lett. 2008 Nov 6;10(21):4747-50. doi: 10.1021/ol801835q. Epub 2008 Oct 7. Org Lett. 2008. PMID: 18837555

7

Adventures in bridgehead substitution chemistry: synthesis of polycyclic polyprenylated acylphloroglucinols (PPAPs).

Simpkins NS. Simpkins NS. Chem Commun (Camb). 2013 Feb 4;49(11):1042-51. doi: 10.1039/c2cc37914g. Chem Commun (Camb). 2013. PMID: 23229029

8

First total synthesis of concavine.

Saint-Dizier F, Simpkins NS. Saint-Dizier F, et al. Among authors: simpkins ns. Chem Sci. 2017 May 1;8(5):3384-3389. doi: 10.1039/c6sc05627j. Epub 2017 Feb 24. Chem Sci. 2017. PMID: 28507709 Free PMC article.

9

Bridgehead lithiation-substitution of bridged ketones, lactones, lactams, and imides: experimental observations and computational insights.

Hayes CJ, Simpkins NS, Kirk DT, Mitchell L, Baudoux J, Blake AJ, Wilson C. Hayes CJ, et al. Among authors: simpkins ns. J Am Chem Soc. 2009 Jun 17;131(23):8196-210. doi: 10.1021/ja9009875. J Am Chem Soc. 2009. PMID: 19507906

10

Rapid access to the Welwitindolinone alkaloid skeleton by cyclization of indolecarboxaldehyde substituted cyclohexanones.

Baudoux J, Blake AJ, Simpkins NS. Baudoux J, et al. Among authors: simpkins ns. Org Lett. 2005 Sep 15;7(19):4087-9. doi: 10.1021/ol051239t. Org Lett. 2005. PMID: 16146358

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