Clark DS - Search Results

1

Active-site motions and polarity enhance catalytic turnover of hydrated subtilisin dissolved in organic solvents.

Hudson EP, Eppler RK, Beaudoin JM, Dordick JS, Reimer JA, Clark DS. Hudson EP, et al. Among authors: clark ds. J Am Chem Soc. 2009 Apr 1;131(12):4294-300. doi: 10.1021/ja806996q. J Am Chem Soc. 2009. PMID: 19317505 Free PMC article.

2

Enzymatic catalysis and dynamics in low-water environments.

Affleck R, Xu ZF, Suzawa V, Focht K, Clark DS, Dordick JS. Affleck R, et al. Among authors: clark ds. Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):1100-4. doi: 10.1073/pnas.89.3.1100. Proc Natl Acad Sci U S A. 1992. PMID: 1310539 Free PMC article.

3

Probing enzymic transition state hydrophobicities.

Wangikar PP, Rich JO, Clark DS, Dordick JS. Wangikar PP, et al. Among authors: clark ds. Biochemistry. 1995 Sep 26;34(38):12302-10. doi: 10.1021/bi00038a026. Biochemistry. 1995. PMID: 7547973

4

Combinatorial biocatalysis: a natural approach to drug discovery.

Michels PC, Khmelnitsky YL, Dordick JS, Clark DS. Michels PC, et al. Among authors: clark ds. Trends Biotechnol. 1998 May;16(5):210-5. doi: 10.1016/s0167-7799(98)01190-1. Trends Biotechnol. 1998. PMID: 9621460 Review.

5

Multinuclear NMR study of enzyme hydration in an organic solvent.

Lee CS, Ru MT, Haake M, Dordick JS, Reimer JA, Clark DS. Lee CS, et al. Among authors: clark ds. Biotechnol Bioeng. 1998 Mar 20;57(6):686-93. Biotechnol Bioeng. 1998. PMID: 10099248

6

Testing for diffusion limitations in salt-activated enzyme catalysts operating in organic solvents.

Bedell BA, Mozhaev VV, Clark DS, Dordick JS. Bedell BA, et al. Among authors: clark ds. Biotechnol Bioeng. 1998 Jun 20;58(6):654-7. Biotechnol Bioeng. 1998. PMID: 10099304

7

Optimizing the salt-induced activation of enzymes in organic solvents: effects of lyophilization time and water content.

Ru MT, Dordick JS, Reimer JA, Clark DS. Ru MT, et al. Among authors: clark ds. Biotechnol Bioeng. 1999 Apr 20;63(2):233-41. doi: 10.1002/(sici)1097-0290(19990420)63:2<233::aid-bit12>3.0.co;2-s. Biotechnol Bioeng. 1999. PMID: 10099600

8

Intrinsic effects of solvent polarity on enzymic activation energies.

Kim J, Clark DS, Dordick JS. Kim J, et al. Among authors: clark ds. Biotechnol Bioeng. 2000 Jan 5;67(1):112-6. doi: 10.1002/(sici)1097-0290(20000105)67:1<112::aid-bit13>3.0.co;2-e. Biotechnol Bioeng. 2000. PMID: 10581442

9

Chemoenzymatic construction of a four-component Ugi combinatorial library.

Liu XC, Clark DS, Dordick JS. Liu XC, et al. Among authors: clark ds. Biotechnol Bioeng. 2000 Aug 20;69(4):457-60. Biotechnol Bioeng. 2000. PMID: 10862684

10

Siloxane-based biocatalytic films and paints for use as reactive coatings.

Kim Y, Dordick J, Clark D. Kim Y, et al. Biotechnol Bioeng. 2001 Feb 20;72(4):475-82. doi: 10.1002/1097-0290(20010220)72:4<475::aid-bit1009>3.0.co;2-f. Biotechnol Bioeng. 2001. PMID: 11180067

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