Rajapurohitam V - Search Results

1

Anti-hypertrophic effect of NHE-1 inhibition involves GSK-3beta-dependent attenuation of mitochondrial dysfunction.

Javadov S, Rajapurohitam V, Kilić A, Zeidan A, Choi A, Karmazyn M. Javadov S, et al. Among authors: rajapurohitam v. J Mol Cell Cardiol. 2009 Jun;46(6):998-1007. doi: 10.1016/j.yjmcc.2008.12.023. Epub 2009 Jan 20. J Mol Cell Cardiol. 2009. PMID: 19318234

2

Inhibition of phenylephrine induced hypertrophy in rat neonatal cardiomyocytes by the mitochondrial KATP channel opener diazoxide.

Xia Y, Rajapurohitam V, Cook MA, Karmazyn M. Xia Y, et al. Among authors: rajapurohitam v. J Mol Cell Cardiol. 2004 Nov;37(5):1063-7. doi: 10.1016/j.yjmcc.2004.07.002. J Mol Cell Cardiol. 2004. PMID: 15522283

3

Antihypertrophic effect of Na+/H+ exchanger isoform 1 inhibition is mediated by reduced mitogen-activated protein kinase activation secondary to improved mitochondrial integrity and decreased generation of mitochondrial-derived reactive oxygen species.

Javadov S, Baetz D, Rajapurohitam V, Zeidan A, Kirshenbaum LA, Karmazyn M. Javadov S, et al. Among authors: rajapurohitam v. J Pharmacol Exp Ther. 2006 Jun;317(3):1036-43. doi: 10.1124/jpet.105.100107. Epub 2006 Mar 2. J Pharmacol Exp Ther. 2006. PMID: 16513848

4

An autocrine role for leptin in mediating the cardiomyocyte hypertrophic effects of angiotensin II and endothelin-1.

Rajapurohitam V, Javadov S, Purdham DM, Kirshenbaum LA, Karmazyn M. Rajapurohitam V, et al. J Mol Cell Cardiol. 2006 Aug;41(2):265-74. doi: 10.1016/j.yjmcc.2006.05.001. Epub 2006 Jun 23. J Mol Cell Cardiol. 2006. PMID: 16806260

5

NHE-1 inhibition-induced cardioprotection against ischaemia/reperfusion is associated with attenuation of the mitochondrial permeability transition.

Javadov S, Choi A, Rajapurohitam V, Zeidan A, Basnakian AG, Karmazyn M. Javadov S, et al. Among authors: rajapurohitam v. Cardiovasc Res. 2008 Jan 15;77(2):416-24. doi: 10.1093/cvr/cvm039. Epub 2007 Oct 18. Cardiovasc Res. 2008. PMID: 18006455

6

Nitric oxide inhibits endothelin-1-induced neonatal cardiomyocyte hypertrophy via a RhoA-ROCK-dependent pathway.

Hunter JC, Zeidan A, Javadov S, Kilić A, Rajapurohitam V, Karmazyn M. Hunter JC, et al. Among authors: rajapurohitam v. J Mol Cell Cardiol. 2009 Dec;47(6):810-8. doi: 10.1016/j.yjmcc.2009.09.012. Epub 2009 Sep 30. J Mol Cell Cardiol. 2009. PMID: 19799911

7

A novel chimeric natriuretic peptide reduces cardiomyocyte hypertrophy through the NHE-1-calcineurin pathway.

Kilic A, Rajapurohitam V, Sandberg SM, Zeidan A, Hunter JC, Said Faruq N, Lee CY, Burnett JC Jr, Karmazyn M. Kilic A, et al. Among authors: rajapurohitam v. Cardiovasc Res. 2010 Dec 1;88(3):434-42. doi: 10.1093/cvr/cvq254. Epub 2010 Aug 2. Cardiovasc Res. 2010. PMID: 20679416 Free PMC article.

8

Expression of mitochondrial fusion-fission proteins during post-infarction remodeling: the effect of NHE-1 inhibition.

Javadov S, Rajapurohitam V, Kilić A, Hunter JC, Zeidan A, Said Faruq N, Escobales N, Karmazyn M. Javadov S, et al. Among authors: rajapurohitam v. Basic Res Cardiol. 2011 Jan;106(1):99-109. doi: 10.1007/s00395-010-0122-3. Epub 2010 Oct 1. Basic Res Cardiol. 2011. PMID: 20886221

9

Ginseng inhibits cardiomyocyte hypertrophy and heart failure via NHE-1 inhibition and attenuation of calcineurin activation.

Guo J, Gan XT, Haist JV, Rajapurohitam V, Zeidan A, Faruq NS, Karmazyn M. Guo J, et al. Among authors: rajapurohitam v. Circ Heart Fail. 2011 Jan;4(1):79-88. doi: 10.1161/CIRCHEARTFAILURE.110.957969. Epub 2010 Oct 22. Circ Heart Fail. 2011. PMID: 20971938

10

Ouabain increases iNOS-dependent nitric oxide generation which contributes to the hypertrophic effect of the glycoside: possible role of peroxynitrite formation.

Gan XT, Hunter JC, Huang C, Xue J, Rajapurohitam V, Javadov S, Karmazyn M. Gan XT, et al. Among authors: rajapurohitam v. Mol Cell Biochem. 2012 Apr;363(1-2):323-33. doi: 10.1007/s11010-011-1185-7. Epub 2011 Dec 10. Mol Cell Biochem. 2012. PMID: 22160804

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