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Structure-activity relationships of the cycloalkanol ethylamine scaffold: discovery of selective norepinephrine reuptake inhibitors.
Mahaney PE, Gavrin LK, Trybulski EJ, Stack GP, Vu TA, Cohn ST, Ye F, Belardi JK, Santilli AA, Sabatucci JP, Leiter J, Johnston GH, Bray JA, Burroughs KD, Cosmi SA, Leventhal L, Koury EJ, Zhang Y, Mugford CA, Ho DM, Rosenzweig-Lipson SJ, Platt B, Smith VA, Deecher DC. Mahaney PE, et al. Among authors: leiter j. J Med Chem. 2008 Jul 10;51(13):4038-49. doi: 10.1021/jm8002262. Epub 2008 Jun 17. J Med Chem. 2008. PMID: 18557608
Heterocyclic cycloalkanol ethylamines as norepinephrine reuptake inhibitors.
Sabatucci JP, Mahaney PE, Leiter J, Johnston G, Burroughs K, Cosmi S, Zhang Y, Ho D, Deecher DC, Trybulski E. Sabatucci JP, et al. Among authors: leiter j. Bioorg Med Chem Lett. 2010 May 1;20(9):2809-12. doi: 10.1016/j.bmcl.2010.03.059. Epub 2010 Mar 15. Bioorg Med Chem Lett. 2010. PMID: 20378347
Discovery of WAY-260022, a Potent and Selective Inhibitor of the Norepinephrine Transporter.
Gavrin LK, Mahaney PE, Jenkins D, Nogle LM, Mugford CA, Huselton C, Leiter J, Johnston GH, Bray JA, Burroughs KD, Cosmi SA, Alfinito P, Ho DM, Deecher DC, Trybulski EJ. Gavrin LK, et al. Among authors: leiter j. ACS Med Chem Lett. 2010 Mar 25;1(3):91-5. doi: 10.1021/ml100009p. eCollection 2010 Jun 10. ACS Med Chem Lett. 2010. PMID: 24900182 Free PMC article.
Clinical validation of a wireless patch-based polysomnography system.
Viniol C, Galetke W, Woehrle H, Nilius G, Schöbel C, Randerath W, Leiter J, Canisius S, Schneider H. Viniol C, et al. Among authors: leiter j. J Clin Sleep Med. 2025 Jan 7. doi: 10.5664/jcsm.11524. Online ahead of print. J Clin Sleep Med. 2025. PMID: 39773950
Altered 5-HT2A/C receptor binding in the medulla oblongata in the sudden infant death syndrome (SIDS): Part II. Age-associated alterations in serotonin receptor binding profiles within medullary nuclei supporting cardiorespiratory homeostasis.
Cummings KJ, Leiter JC, Trachtenberg FL, Okaty BW, Darnall RA, Haas EA, Harper RM, Nattie EE, Krous HF, Mena OJ, Richerson GB, Dymecki SM, Kinney HC, Haynes RL. Cummings KJ, et al. Among authors: leiter jc. J Neuropathol Exp Neurol. 2024 Feb 21;83(3):144-160. doi: 10.1093/jnen/nlae004. J Neuropathol Exp Neurol. 2024. PMID: 38323418 Free PMC article.
352 results