Zhang P - Search Results

1

3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors.

Vu AT, Cohn ST, Terefenko EA, Moore WJ, Zhang P, Mahaney PE, Trybulski EJ, Goljer I, Dooley R, Bray JA, Johnston GH, Leiter J, Deecher DC. Vu AT, et al. Among authors: zhang p. Bioorg Med Chem Lett. 2009 May 1;19(9):2464-7. doi: 10.1016/j.bmcl.2009.03.054. Epub 2009 Mar 18. Bioorg Med Chem Lett. 2009. PMID: 19329313

2

Potent nonsteroidal progesterone receptor agonists: synthesis and SAR study of 6-aryl benzoxazines.

Zhang P, Terefenko EA, Fensome A, Zhang Z, Zhu Y, Cohen J, Winneker R, Wrobel J, Yardley J. Zhang P, et al. Among authors: zhang z. Bioorg Med Chem Lett. 2002 Mar 11;12(5):787-90. doi: 10.1016/s0960-894x(02)00025-2. Bioorg Med Chem Lett. 2002. PMID: 11859003

3

SAR studies of 6-aryl-1,3-dihydrobenzimidazol-2-ones as progesterone receptor antagonists.

Terefenko EA, Kern J, Fensome A, Wrobel J, Zhu Y, Cohen J, Winneker R, Zhang Z, Zhang P. Terefenko EA, et al. Among authors: zhang p, zhang z. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3600-3. doi: 10.1016/j.bmcl.2005.05.082. Bioorg Med Chem Lett. 2005. PMID: 15978807

4

Synthesis and activity of a new class of dual acting norepinephrine and serotonin reuptake inhibitors: 3-(1H-indol-1-yl)-3-arylpropan-1-amines.

Mahaney PE, Vu AT, McComas CC, Zhang P, Nogle LM, Watts WL, Sarkahian A, Leventhal L, Sullivan NR, Uveges AJ, Trybulski EJ. Mahaney PE, et al. Among authors: zhang p. Bioorg Med Chem. 2006 Dec 15;14(24):8455-66. doi: 10.1016/j.bmc.2006.08.039. Epub 2006 Sep 14. Bioorg Med Chem. 2006. PMID: 16973367

5

SAR studies of 6-(arylamino)-4,4-disubstituted-1-methyl-1,4-dihydro-benzo[d][1,3]oxazin-2-ones as progesterone receptor antagonists.

Kern JC, Terefenko EA, Fensome A, Unwallla R, Wrobel J, Zhu Y, Cohen J, Winneker R, Zhang Z, Zhang P. Kern JC, et al. Among authors: zhang p, zhang z. Bioorg Med Chem Lett. 2007 Jan 1;17(1):189-92. doi: 10.1016/j.bmcl.2006.09.060. Epub 2006 Oct 5. Bioorg Med Chem Lett. 2007. PMID: 17027272

6

1,5-Dihydro-benzo[e][1,4]oxazepin-2(1H)-ones containing a 7-(5'-cyanopyrrol-2-yl) group as nonsteroidal progesterone receptor modulators.

Kern JC, Terefenko EA, Fensome A, Unwalla R, Wrobel J, Cohen J, Zhu Y, Berrodin TJ, Yudt MR, Winneker RC, Zhang Z, Zhang P. Kern JC, et al. Among authors: zhang p, zhang z. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5015-7. doi: 10.1016/j.bmcl.2008.08.015. Epub 2008 Aug 9. Bioorg Med Chem Lett. 2008. PMID: 18722119

7

Synthesis and activity of 1-(3-amino-1-phenylpropyl)indolin-2-ones: a new class of selective norepinephrine reuptake inhibitors.

McComas CC, Vu AT, Mahaney PE, Cohn ST, Fensome A, Marella MA, Nogle L, Trybulski EJ, Ye F, Zhang P, Alfinito P, Bray J, Johnston G, Koury E, Deecher DC. McComas CC, et al. Among authors: zhang p. Bioorg Med Chem Lett. 2008 Sep 15;18(18):4929-31. doi: 10.1016/j.bmcl.2008.08.060. Epub 2008 Aug 22. Bioorg Med Chem Lett. 2008. PMID: 18771916

8

Synthesis and activity of novel 1- or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors.

Zhang P, Terefenko EA, McComas CC, Mahaney PE, Vu A, Trybulski E, Koury E, Johnston G, Bray J, Deecher D. Zhang P, et al. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6067-70. doi: 10.1016/j.bmcl.2008.10.026. Epub 2008 Oct 11. Bioorg Med Chem Lett. 2008. PMID: 18951020

9

Structure-activity relationships of the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ol series of monoamine reuptake inhibitors.

Mahaney PE, Kim CY, Coghlan RD, Cohn ST, Heffernan GD, Huselton CA, Terefenko EA, Vu AT, Zhang P, Burroughs KD, Cosmi SA, Bray JA, Johnston GH, Deecher DC, Trybulski EJ. Mahaney PE, et al. Among authors: zhang p. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5807-10. doi: 10.1016/j.bmcl.2009.07.050. Epub 2009 Aug 25. Bioorg Med Chem Lett. 2009. PMID: 19713106

10

1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: potent, selective, and orally efficacious norepinephrine reuptake inhibitors.

Zhang P, Terefenko EA, Bray J, Deecher D, Fensome A, Harrison J, Kim C, Koury E, Mark L, McComas CC, Mugford CA, Trybulski EJ, Vu AT, Whiteside GT, Mahaney PE. Zhang P, et al. J Med Chem. 2009 Sep 24;52(18):5703-11. doi: 10.1021/jm900888c. J Med Chem. 2009. PMID: 19722525

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