Chiesa R - Search Results

1

Chiesa R, Harris DA. Chiesa R, et al. PLoS Biol. 2009 Mar 31;7(3):e75. doi: 10.1371/journal.pbio.1000075. PLoS Biol. 2009. PMID: 19338390 Free PMC article.

2

Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities.

Chiesa R, Piccardo P, Biasini E, Ghetti B, Harris DA. Chiesa R, et al. J Neurosci. 2008 Dec 3;28(49):13258-67. doi: 10.1523/JNEUROSCI.3109-08.2008. J Neurosci. 2008. PMID: 19052217 Free PMC article.

3

Immunopurification of pathological prion protein aggregates.

Biasini E, Tapella L, Mantovani S, Stravalaci M, Gobbi M, Harris DA, Chiesa R. Biasini E, et al. Among authors: chiesa r. PLoS One. 2009 Nov 12;4(11):e7816. doi: 10.1371/journal.pone.0007816. PLoS One. 2009. PMID: 19915706 Free PMC article.

4

Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway.

Massignan T, Biasini E, Lauranzano E, Veglianese P, Pignataro M, Fioriti L, Harris DA, Salmona M, Chiesa R, Bonetto V. Massignan T, et al. Among authors: chiesa r. Mol Cell Proteomics. 2010 Apr;9(4):611-22. doi: 10.1074/mcp.M900271-MCP200. Epub 2009 Dec 7. Mol Cell Proteomics. 2010. PMID: 19996123 Free PMC article.

5

Prion diseases: what is the neurotoxic molecule?

Chiesa R, Harris DA. Chiesa R, et al. Neurobiol Dis. 2001 Oct;8(5):743-63. doi: 10.1006/nbdi.2001.0433. Neurobiol Dis. 2001. PMID: 11592845 Review.

6

The neurotoxicity of prion protein (PrP) peptide 106-126 is independent of the expression level of PrP and is not mediated by abnormal PrP species.

Fioriti L, Quaglio E, Massignan T, Colombo L, Stewart RS, Salmona M, Harris DA, Forloni G, Chiesa R. Fioriti L, et al. Among authors: chiesa r. Mol Cell Neurosci. 2005 Jan;28(1):165-76. doi: 10.1016/j.mcn.2004.09.006. Mol Cell Neurosci. 2005. PMID: 15607951

7

Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease.

Chiesa R, Piccardo P, Dossena S, Nowoslawski L, Roth KA, Ghetti B, Harris DA. Chiesa R, et al. Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):238-43. doi: 10.1073/pnas.0406173102. Epub 2004 Dec 23. Proc Natl Acad Sci U S A. 2005. PMID: 15618403 Free PMC article.

8

Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations.

Fioriti L, Dossena S, Stewart LR, Stewart RS, Harris DA, Forloni G, Chiesa R. Fioriti L, et al. Among authors: chiesa r. J Biol Chem. 2005 Mar 25;280(12):11320-8. doi: 10.1074/jbc.M412441200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632159 Free article.

9

A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein.

Massignan T, Stewart RS, Biasini E, Solomon IH, Bonetto V, Chiesa R, Harris DA. Massignan T, et al. Among authors: chiesa r. J Biol Chem. 2010 Mar 5;285(10):7752-65. doi: 10.1074/jbc.M109.064949. Epub 2009 Nov 24. J Biol Chem. 2010. PMID: 19940127 Free PMC article.

10

The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells.

Biasini E, Turnbaugh JA, Massignan T, Veglianese P, Forloni G, Bonetto V, Chiesa R, Harris DA. Biasini E, et al. Among authors: chiesa r. PLoS One. 2012;7(3):e33472. doi: 10.1371/journal.pone.0033472. Epub 2012 Mar 12. PLoS One. 2012. PMID: 22428057 Free PMC article.

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