Shock DD - Search Results

1

Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function.

Upton TG, Kashemirov BA, McKenna CE, Goodman MF, Prakash GK, Kultyshev R, Batra VK, Shock DD, Pedersen LC, Beard WA, Wilson SH. Upton TG, et al. Among authors: shock dd. Org Lett. 2009 May 7;11(9):1883-6. doi: 10.1021/ol701755k. Org Lett. 2009. PMID: 19351147 Free PMC article.

2

Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid.

Surya Prakash GK, Zibinsky M, Upton TG, Kashemirov BA, McKenna CE, Oertell K, Goodman MF, Batra VK, Pedersen LC, Beard WA, Shock DD, Wilson SH, Olah GA. Surya Prakash GK, et al. Among authors: shock dd. Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15693-8. doi: 10.1073/pnas.1007430107. Epub 2010 Aug 19. Proc Natl Acad Sci U S A. 2010. PMID: 20724659 Free PMC article.

3

Stereospecific formation of a ternary complex of (S)-α,β-fluoromethylene-dATP with DNA pol β.

Chamberlain BT, Batra VK, Beard WA, Kadina AP, Shock DD, Kashemirov BA, McKenna CE, Goodman MF, Wilson SH. Chamberlain BT, et al. Among authors: shock dd. Chembiochem. 2012 Mar 5;13(4):528-30. doi: 10.1002/cbic.201100738. Epub 2012 Feb 7. Chembiochem. 2012. PMID: 22315190 Free PMC article.

4

Effect of β,γ-CHF- and β,γ-CHCl-dGTP halogen atom stereochemistry on the transition state of DNA polymerase β.

Oertell K, Wu Y, Zakharova VM, Kashemirov BA, Shock DD, Beard WA, Wilson SH, McKenna CE, Goodman MF. Oertell K, et al. Among authors: shock dd. Biochemistry. 2012 Oct 30;51(43):8491-501. doi: 10.1021/bi3010335. Epub 2012 Oct 19. Biochemistry. 2012. PMID: 23043620 Free PMC article.

5

Influence of DNA structure on DNA polymerase beta active site function: extension of mutagenic DNA intermediates.

Beard WA, Shock DD, Wilson SH. Beard WA, et al. Among authors: shock dd. J Biol Chem. 2004 Jul 23;279(30):31921-9. doi: 10.1074/jbc.M404016200. Epub 2004 May 15. J Biol Chem. 2004. PMID: 15145936 Free article.

6

Nucleotide-induced DNA polymerase active site motions accommodating a mutagenic DNA intermediate.

Batra VK, Beard WA, Shock DD, Pedersen LC, Wilson SH. Batra VK, et al. Among authors: shock dd. Structure. 2005 Aug;13(8):1225-33. doi: 10.1016/j.str.2005.05.010. Structure. 2005. PMID: 16084394 Free article.

7

Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation.

Batra VK, Beard WA, Shock DD, Pedersen LC, Wilson SH. Batra VK, et al. Among authors: shock dd. Mol Cell. 2008 May 9;30(3):315-24. doi: 10.1016/j.molcel.2008.02.025. Mol Cell. 2008. PMID: 18471977 Free PMC article.

8

Alpha,beta-methylene-2'-deoxynucleoside 5'-triphosphates as noncleavable substrates for DNA polymerases: isolation, characterization, and stability studies of novel 2'-deoxycyclonucleosides, 3,5'-cyclo-dG, and 2,5'-cyclo-dT.

Liang F, Jain N, Hutchens T, Shock DD, Beard WA, Wilson SH, Chiarelli MP, Cho BP. Liang F, et al. Among authors: shock dd. J Med Chem. 2008 Oct 23;51(20):6460-70. doi: 10.1021/jm800692a. Epub 2008 Sep 24. J Med Chem. 2008. PMID: 18811136 Free PMC article.

9

DNA polymerase beta substrate specificity: side chain modulation of the "A-rule".

Beard WA, Shock DD, Batra VK, Pedersen LC, Wilson SH. Beard WA, et al. Among authors: shock dd. J Biol Chem. 2009 Nov 13;284(46):31680-9. doi: 10.1074/jbc.M109.029843. Epub 2009 Sep 15. J Biol Chem. 2009. PMID: 19759017 Free PMC article.

10

Loss of DNA polymerase beta stacking interactions with templating purines, but not pyrimidines, alters catalytic efficiency and fidelity.

Beard WA, Shock DD, Yang XP, DeLauder SF, Wilson SH. Beard WA, et al. Among authors: shock dd. J Biol Chem. 2002 Mar 8;277(10):8235-42. doi: 10.1074/jbc.M107286200. Epub 2001 Dec 26. J Biol Chem. 2002. PMID: 11756435 Free article.

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