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A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance.
Newgard CB, An J, Bain JR, Muehlbauer MJ, Stevens RD, Lien LF, Haqq AM, Shah SH, Arlotto M, Slentz CA, Rochon J, Gallup D, Ilkayeva O, Wenner BR, Yancy WS Jr, Eisenson H, Musante G, Surwit RS, Millington DS, Butler MD, Svetkey LP. Newgard CB, et al. Among authors: an j. Cell Metab. 2009 Apr;9(4):311-26. doi: 10.1016/j.cmet.2009.02.002. Cell Metab. 2009. PMID: 19356713 Free PMC article.
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.
Koves TR, Li P, An J, Akimoto T, Slentz D, Ilkayeva O, Dohm GL, Yan Z, Newgard CB, Muoio DM. Koves TR, et al. Among authors: an j. J Biol Chem. 2005 Sep 30;280(39):33588-98. doi: 10.1074/jbc.M507621200. Epub 2005 Aug 3. J Biol Chem. 2005. PMID: 16079133 Free article.
The coactivator SRC-1 is an essential coordinator of hepatic glucose production.
Louet JF, Chopra AR, Sagen JV, An J, York B, Tannour-Louet M, Saha PK, Stevens RD, Wenner BR, Ilkayeva OR, Bain JR, Zhou S, DeMayo F, Xu J, Newgard CB, O'Malley BW. Louet JF, et al. Among authors: an j. Cell Metab. 2010 Dec 1;12(6):606-18. doi: 10.1016/j.cmet.2010.11.009. Cell Metab. 2010. PMID: 21109193 Free PMC article.
Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability.
Horn SR, Thomenius MJ, Johnson ES, Freel CD, Wu JQ, Coloff JL, Yang CS, Tang W, An J, Ilkayeva OR, Rathmell JC, Newgard CB, Kornbluth S. Horn SR, et al. Among authors: an j. Mol Biol Cell. 2011 Apr 15;22(8):1207-16. doi: 10.1091/mbc.E10-07-0567. Epub 2011 Feb 16. Mol Biol Cell. 2011. PMID: 21325626 Free PMC article.
Obesity and lipid stress inhibit carnitine acetyltransferase activity.
Seiler SE, Martin OJ, Noland RC, Slentz DH, DeBalsi KL, Ilkayeva OR, An J, Newgard CB, Koves TR, Muoio DM. Seiler SE, et al. Among authors: an j. J Lipid Res. 2014 Apr;55(4):635-44. doi: 10.1194/jlr.M043448. Epub 2014 Jan 6. J Lipid Res. 2014. PMID: 24395925 Free PMC article.
6,074 results