Lucet IS - Search Results

1

Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.

Williams NK, Bamert RS, Patel O, Wang C, Walden PM, Wilks AF, Fantino E, Rossjohn J, Lucet IS. Williams NK, et al. Among authors: lucet is. J Mol Biol. 2009 Mar 20;387(1):219-32. doi: 10.1016/j.jmb.2009.01.041. Epub 2009 Jan 29. J Mol Biol. 2009. PMID: 19361440

2

Molecular dissection of the pseudokinase ZED1 expands effector recognition to the tomato immune receptor ZAR1.

Diplock N, Baudin M, Xiang XD, Liang LY, Dai W, Murphy JM, Lucet IS, Hassan JA, Lewis JD. Diplock N, et al. Among authors: lucet is. Plant Physiol. 2024 Sep 2;196(1):651-666. doi: 10.1093/plphys/kiae268. Plant Physiol. 2024. PMID: 38748589

3

Identification of the structural and functional domains of the large serine recombinase TnpX from Clostridium perfringens.

Lucet IS, Tynan FE, Adams V, Rossjohn J, Lyras D, Rood JI. Lucet IS, et al. J Biol Chem. 2005 Jan 28;280(4):2503-11. doi: 10.1074/jbc.M409702200. Epub 2004 Nov 12. J Biol Chem. 2005. PMID: 15542858 Free article.

4

The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor.

Lucet IS, Fantino E, Styles M, Bamert R, Patel O, Broughton SE, Walter M, Burns CJ, Treutlein H, Wilks AF, Rossjohn J. Lucet IS, et al. Blood. 2006 Jan 1;107(1):176-83. doi: 10.1182/blood-2005-06-2413. Epub 2005 Sep 20. Blood. 2006. PMID: 16174768 Free article.

5

Two distinct regions of the large serine recombinase TnpX are required for DNA binding and biological function.

Adams V, Lucet IS, Tynan FE, Chiarezza M, Howarth PM, Kim J, Rossjohn J, Lyras D, Rood JI. Adams V, et al. Among authors: lucet is. Mol Microbiol. 2006 May;60(3):591-601. doi: 10.1111/j.1365-2958.2006.05120.x. Mol Microbiol. 2006. PMID: 16629663 Free article.

6

Hijacking of a substrate-binding protein scaffold for use in mycobacterial cell wall biosynthesis.

Marland Z, Beddoe T, Zaker-Tabrizi L, Lucet IS, Brammananth R, Whisstock JC, Wilce MC, Coppel RL, Crellin PK, Rossjohn J. Marland Z, et al. Among authors: lucet is. J Mol Biol. 2006 Jun 16;359(4):983-97. doi: 10.1016/j.jmb.2006.04.012. Epub 2006 Apr 25. J Mol Biol. 2006. PMID: 16698034

7

The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain.

Walter M, Lucet IS, Patel O, Broughton SE, Bamert R, Williams NK, Fantino E, Wilks AF, Rossjohn J. Walter M, et al. Among authors: lucet is. J Mol Biol. 2007 Mar 30;367(3):839-47. doi: 10.1016/j.jmb.2007.01.036. Epub 2007 Jan 20. J Mol Biol. 2007. PMID: 17292918

8

Crystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound state.

Williams NK, Lucet IS, Klinken SP, Ingley E, Rossjohn J. Williams NK, et al. Among authors: lucet is. J Biol Chem. 2009 Jan 2;284(1):284-291. doi: 10.1074/jbc.M807850200. Epub 2008 Nov 4. J Biol Chem. 2009. PMID: 18984583 Free article.

9

Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors.

Pellicci DG, Patel O, Kjer-Nielsen L, Pang SS, Sullivan LC, Kyparissoudis K, Brooks AG, Reid HH, Gras S, Lucet IS, Koh R, Smyth MJ, Mallevaey T, Matsuda JL, Gapin L, McCluskey J, Godfrey DI, Rossjohn J. Pellicci DG, et al. Among authors: lucet is. Immunity. 2009 Jul 17;31(1):47-59. doi: 10.1016/j.immuni.2009.04.018. Immunity. 2009. PMID: 19592275 Free PMC article.

10

Plasmodium kinases as targets for new-generation antimalarials.

Lucet IS, Tobin A, Drewry D, Wilks AF, Doerig C. Lucet IS, et al. Future Med Chem. 2012 Dec;4(18):2295-310. doi: 10.4155/fmc.12.183. Future Med Chem. 2012. PMID: 23234552 Review.

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