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Discovery of thioether-bridged cyclic pentapeptides binding to Grb2-SH2 domain with high affinity.
Bioorg Med Chem Lett. 2009 May 15;19(10):2693-8. doi: 10.1016/j.bmcl.2009.03.134. Epub 2009 Mar 29.
Bioorg Med Chem Lett. 2009.
PMID: 19362470
Free PMC article.
Structure-based design of potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.
Jiang S, Li P, Peach ML, Bindu L, Worthy KW, Fisher RJ, Burke TR Jr, Nicklaus M, Roller PP.
Jiang S, et al. Among authors: worthy kw.
Biochem Biophys Res Commun. 2006 Oct 20;349(2):497-503. doi: 10.1016/j.bbrc.2006.08.059. Epub 2006 Aug 22.
Biochem Biophys Res Commun. 2006.
PMID: 16945340
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