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Heme-oxygenase-1 induction and carbon monoxide-releasing molecule inhibit lipopolysaccharide (LPS)-induced high-mobility group box 1 release in vitro and improve survival of mice in LPS- and cecal ligation and puncture-induced sepsis model in vivo.
Tsoyi K, Lee TY, Lee YS, Kim HJ, Seo HG, Lee JH, Chang KC. Tsoyi K, et al. Among authors: kim hj. Mol Pharmacol. 2009 Jul;76(1):173-82. doi: 10.1124/mol.109.055137. Epub 2009 Apr 14. Mol Pharmacol. 2009. PMID: 19366789
Anthocyanins from soybean seed coat inhibit the expression of TNF-alpha-induced genes associated with ischemia/reperfusion in endothelial cell by NF-kappaB-dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo.
Kim HJ, Tsoy I, Park JM, Chung JI, Shin SC, Chang KC. Kim HJ, et al. FEBS Lett. 2006 Feb 20;580(5):1391-7. doi: 10.1016/j.febslet.2006.01.062. Epub 2006 Jan 26. FEBS Lett. 2006. PMID: 16457818 Free article.
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