Gobec S - Search Results

1

Discovery of novel benzene 1,3-dicarboxylic acid inhibitors of bacterial MurD and MurE ligases by structure-based virtual screening approach.

Perdih A, Kovac A, Wolber G, Blanot D, Gobec S, Solmajer T. Perdih A, et al. Among authors: gobec s. Bioorg Med Chem Lett. 2009 May 15;19(10):2668-73. doi: 10.1016/j.bmcl.2009.03.141. Epub 2009 Apr 1. Bioorg Med Chem Lett. 2009. PMID: 19369074

2

Synthesis and biochemical evaluation of some novel N-acyl phosphono- and phosphinoalanine derivatives as potential inhibitors of the D-glutamic acid-adding enzyme.

Gobec S, Urleb U, Auger G, Blanot D. Gobec S, et al. Pharmazie. 2001 Apr;56(4):295-7. Pharmazie. 2001. PMID: 11338666

3

Phosphonate inhibitors of antigen 85C, a crucial enzyme involved in the biosynthesis of the Mycobacterium tuberculosis cell wall.

Gobec S, Plantan I, Mravljak J, Wilson RA, Besra GS, Kikelj D. Gobec S, et al. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3559-62. doi: 10.1016/j.bmcl.2004.04.052. Bioorg Med Chem Lett. 2004. PMID: 15177473

4

Cinnamic acid esters as potent inhibitors of fungal 17beta-hydroxysteroid dehydrogenase--a model enzyme of the short-chain dehydrogenase/reductase superfamily.

Gobec S, Sova M, Kristan K, Rizner TL. Gobec S, et al. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3933-6. doi: 10.1016/j.bmcl.2004.05.069. Bioorg Med Chem Lett. 2004. PMID: 15225701

5

Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.

Gobec S, Brozic P, Rizner TL. Gobec S, et al. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5170-5. doi: 10.1016/j.bmcl.2005.08.063. Epub 2005 Sep 23. Bioorg Med Chem Lett. 2005. PMID: 16183274

6

Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD.

Strancar K, Blanot D, Gobec S. Strancar K, et al. Among authors: gobec s. Bioorg Med Chem Lett. 2006 Jan 15;16(2):343-8. doi: 10.1016/j.bmcl.2005.09.086. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16271472

7

Flavonoids and cinnamic acid esters as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase: a synthesis, QSAR and modelling study.

Sova M, Perdih A, Kotnik M, Kristan K, Rizner TL, Solmajer T, Gobec S. Sova M, et al. Among authors: gobec s. Bioorg Med Chem. 2006 Nov 15;14(22):7404-18. doi: 10.1016/j.bmc.2006.07.027. Epub 2006 Aug 7. Bioorg Med Chem. 2006. PMID: 16891119

8

Inhibitors of cathepsin B.

Frlan R, Gobec S. Frlan R, et al. Among authors: gobec s. Curr Med Chem. 2006;13(19):2309-27. doi: 10.2174/092986706777935122. Curr Med Chem. 2006. PMID: 16918357 Review.

9

Design, synthesis, biochemical evaluation and antimycobacterial action of phosphonate inhibitors of antigen 85C, a crucial enzyme involved in biosynthesis of the mycobacterial cell wall.

Gobec S, Plantan I, Mravljak J, Svajger U, Wilson RA, Besra GS, Soares SL, Appelberg R, Kikelj D. Gobec S, et al. Eur J Med Chem. 2007 Jan;42(1):54-63. doi: 10.1016/j.ejmech.2006.08.007. Epub 2006 Sep 28. Eur J Med Chem. 2007. PMID: 17010479

10

New lipophilic phthalimido- and 3-phenoxybenzyl sulfonates: inhibition of antigen 85C mycolyltransferase activity and cytotoxicity.

Kovac A, Wilson RA, Besra GS, Filipic M, Kikelj D, Gobec S. Kovac A, et al. Among authors: gobec s. J Enzyme Inhib Med Chem. 2006 Aug;21(4):391-7. doi: 10.1080/14756360600703214. J Enzyme Inhib Med Chem. 2006. PMID: 17059171 Free article.

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