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Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity.
Cao J, Schulte J, Knight A, Leslie NR, Zagozdzon A, Bronson R, Manevich Y, Beeson C, Neumann CA. Cao J, et al. Among authors: leslie nr. EMBO J. 2009 May 20;28(10):1505-17. doi: 10.1038/emboj.2009.101. Epub 2009 Apr 16. EMBO J. 2009. PMID: 19369943 Free PMC article.
MC1R is a potent regulator of PTEN after UV exposure in melanocytes.
Cao J, Wan L, Hacker E, Dai X, Lenna S, Jimenez-Cervantes C, Wang Y, Leslie NR, Xu GX, Widlund HR, Ryu B, Alani RM, Dutton-Regester K, Goding CR, Hayward NK, Wei W, Cui R. Cao J, et al. Among authors: leslie nr. Mol Cell. 2013 Aug 22;51(4):409-22. doi: 10.1016/j.molcel.2013.08.010. Mol Cell. 2013. PMID: 23973372 Free PMC article.
The regulation of cell migration by PTEN.
Leslie NR, Yang X, Downes CP, Weijer CJ. Leslie NR, et al. Biochem Soc Trans. 2005 Dec;33(Pt 6):1507-8. doi: 10.1042/BST0331507. Biochem Soc Trans. 2005. PMID: 16246156 Review.
Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.
Steelman LS, Navolanic PM, Sokolosky ML, Taylor JR, Lehmann BD, Chappell WH, Abrams SL, Wong EW, Stadelman KM, Terrian DM, Leslie NR, Martelli AM, Stivala F, Libra M, Franklin RA, McCubrey JA. Steelman LS, et al. Among authors: leslie nr. Oncogene. 2008 Jul 3;27(29):4086-95. doi: 10.1038/onc.2008.49. Epub 2008 Mar 10. Oncogene. 2008. PMID: 18332865 Free PMC article.
105 results