Oude Elferink RP - Search Results

1

Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, de Waart DR, van de Wetering K, van der Kruijssen CM, Oude Elferink RP, van Tellingen O, Schinkel AH. Vlaming ML, et al. Among authors: oude elferink rp. Clin Cancer Res. 2009 May 1;15(9):3084-93. doi: 10.1158/1078-0432.CCR-08-2940. Epub 2009 Apr 21. Clin Cancer Res. 2009. PMID: 19383815

2

Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, van Tellingen O, de Waart DR, Oude Elferink RP, van de Wetering K, Schinkel AH. Vlaming ML, et al. Among authors: oude elferink rp. Clin Cancer Res. 2008 Dec 15;14(24):8152-60. doi: 10.1158/1078-0432.CCR-08-1609. Clin Cancer Res. 2008. PMID: 19088030

3

Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.

de Waart DR, Vlaming ML, Kunne C, Schinkel AH, Oude Elferink RP. de Waart DR, et al. Among authors: oude elferink rp. Drug Metab Dispos. 2009 Aug;37(8):1698-702. doi: 10.1124/dmd.108.026146. Epub 2009 May 14. Drug Metab Dispos. 2009. PMID: 19443695

4

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease.

Smit JJ, Schinkel AH, Oude Elferink RP, Groen AK, Wagenaar E, van Deemter L, Mol CA, Ottenhoff R, van der Lugt NM, van Roon MA, et al. Smit JJ, et al. Among authors: oude elferink rp. Cell. 1993 Nov 5;75(3):451-62. doi: 10.1016/0092-8674(93)90380-9. Cell. 1993. PMID: 8106172

5

Multidrug resistance associated protein 2 mediates transport of prostaglandin E2.

de Waart DR, Paulusma CC, Kunne C, Oude Elferink RP. de Waart DR, et al. Among authors: oude elferink rp. Liver Int. 2006 Apr;26(3):362-8. doi: 10.1111/j.1478-3231.2005.01234.x. Liver Int. 2006. PMID: 16584400

6

Hepatic transport mechanisms of cholyl-L-lysyl-fluorescein.

de Waart DR, Häusler S, Vlaming ML, Kunne C, Hänggi E, Gruss HJ, Oude Elferink RP, Stieger B. de Waart DR, et al. Among authors: oude elferink rp. J Pharmacol Exp Ther. 2010 Jul;334(1):78-86. doi: 10.1124/jpet.110.166991. Epub 2010 Apr 13. J Pharmacol Exp Ther. 2010. PMID: 20388726

7

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.

van de Steeg E, Stránecký V, Hartmannová H, Nosková L, Hřebíček M, Wagenaar E, van Esch A, de Waart DR, Oude Elferink RP, Kenworthy KE, Sticová E, al-Edreesi M, Knisely AS, Kmoch S, Jirsa M, Schinkel AH. van de Steeg E, et al. Among authors: oude elferink rp. J Clin Invest. 2012 Feb;122(2):519-28. doi: 10.1172/JCI59526. Epub 2012 Jan 9. J Clin Invest. 2012. PMID: 22232210 Free PMC article.

8

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells.

Evers R, Zaman GJ, van Deemter L, Jansen H, Calafat J, Oomen LC, Oude Elferink RP, Borst P, Schinkel AH. Evers R, et al. Among authors: oude elferink rp. J Clin Invest. 1996 Mar 1;97(5):1211-8. doi: 10.1172/JCI118535. J Clin Invest. 1996. PMID: 8636432 Free PMC article.

9

Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice.

Smith AJ, de Vree JM, Ottenhoff R, Oude Elferink RP, Schinkel AH, Borst P. Smith AJ, et al. Among authors: oude elferink rp. Hepatology. 1998 Aug;28(2):530-6. doi: 10.1002/hep.510280234. Hepatology. 1998. PMID: 9696021

10

Role of MRP2 and GSH in intrahepatic cycling of toxins.

Dietrich CG, Ottenhoff R, de Waart DR, Oude Elferink RP. Dietrich CG, et al. Among authors: oude elferink rp. Toxicology. 2001 Oct 5;167(1):73-81. doi: 10.1016/s0300-483x(01)00459-0. Toxicology. 2001. PMID: 11557131

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