Schinkel AH - Search Results

1

Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, de Waart DR, van de Wetering K, van der Kruijssen CM, Oude Elferink RP, van Tellingen O, Schinkel AH. Vlaming ML, et al. Among authors: schinkel ah. Clin Cancer Res. 2009 May 1;15(9):3084-93. doi: 10.1158/1078-0432.CCR-08-2940. Epub 2009 Apr 21. Clin Cancer Res. 2009. PMID: 19383815

2

Characterization of the human MDR3 P-glycoprotein and its recognition by P-glycoprotein-specific monoclonal antibodies.

Schinkel AH, Roelofs EM, Borst P. Schinkel AH, et al. Cancer Res. 1991 May 15;51(10):2628-35. Cancer Res. 1991. PMID: 1673638

3

Regulation of protein secretion into bile: studies in mice with a disrupted mdr2 p-glycoprotein gene.

Groen AK, Van Wijland MJ, Frederiks WM, Smit JJ, Schinkel AH, Oude Elferink RP. Groen AK, et al. Among authors: schinkel ah. Gastroenterology. 1995 Dec;109(6):1997-2006. doi: 10.1016/0016-5085(95)90768-8. Gastroenterology. 1995. PMID: 7498666

4

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

Schinkel AH, Wagenaar E, van Deemter L, Mol CA, Borst P. Schinkel AH, et al. J Clin Invest. 1995 Oct;96(4):1698-705. doi: 10.1172/JCI118214. J Clin Invest. 1995. PMID: 7560060 Free PMC article.

5

Multidrug resistance and the role of P-glycoprotein knockout mice.

Schinkel AH, Mol CA, Wagenaar E, van Deemter L, Smit JJ, Borst P. Schinkel AH, et al. Eur J Cancer. 1995 Jul-Aug;31A(7-8):1295-8. doi: 10.1016/0959-8049(95)00130-b. Eur J Cancer. 1995. PMID: 7577039 Review.

6

Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.

Oude Elferink RP, Ottenhoff R, van Wijland M, Smit JJ, Schinkel AH, Groen AK. Oude Elferink RP, et al. Among authors: schinkel ah. J Clin Invest. 1995 Jan;95(1):31-8. doi: 10.1172/JCI117658. J Clin Invest. 1995. PMID: 7814632 Free PMC article.

7

Characterization of the promoter region of the human MDR3 P-glycoprotein gene.

Smit JJ, Mol CA, van Deemter L, Wagenaar E, Schinkel AH, Borst P. Smit JJ, et al. Among authors: schinkel ah. Biochim Biophys Acta. 1995 Mar 14;1261(1):44-56. doi: 10.1016/0167-4781(94)00214-n. Biochim Biophys Acta. 1995. PMID: 7893760

8

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs.

Schinkel AH, Smit JJ, van Tellingen O, Beijnen JH, Wagenaar E, van Deemter L, Mol CA, van der Valk MA, Robanus-Maandag EC, te Riele HP, et al. Schinkel AH, et al. Cell. 1994 May 20;77(4):491-502. doi: 10.1016/0092-8674(94)90212-7. Cell. 1994. PMID: 7910522

9

Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals.

Borst P, Schinkel AH, Smit JJ, Wagenaar E, Van Deemter L, Smith AJ, Eijdems EW, Baas F, Zaman GJ. Borst P, et al. Among authors: schinkel ah. Pharmacol Ther. 1993 Nov;60(2):289-99. doi: 10.1016/0163-7258(93)90011-2. Pharmacol Ther. 1993. PMID: 7912835 Review.

10

Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis.

Mauad TH, van Nieuwkerk CM, Dingemans KP, Smit JJ, Schinkel AH, Notenboom RG, van den Bergh Weerman MA, Verkruisen RP, Groen AK, Oude Elferink RP, et al. Mauad TH, et al. Among authors: schinkel ah. Am J Pathol. 1994 Nov;145(5):1237-45. Am J Pathol. 1994. PMID: 7977654 Free PMC article.

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