Chen EX - Search Results

1

Phase I study of MG98, an oligonucleotide antisense inhibitor of human DNA methyltransferase 1, given as a 7-day infusion in patients with advanced solid tumors.

Plummer R, Vidal L, Griffin M, Lesley M, de Bono J, Coulthard S, Sludden J, Siu LL, Chen EX, Oza AM, Reid GK, McLeod AR, Besterman JM, Lee C, Judson I, Calvert H, Boddy AV. Plummer R, et al. Among authors: chen ex. Clin Cancer Res. 2009 May 1;15(9):3177-83. doi: 10.1158/1078-0432.CCR-08-2859. Epub 2009 Apr 21. Clin Cancer Res. 2009. PMID: 19383817 Free article. Clinical Trial.

2

Simultaneous determination of OSI-774 and its major metabolite OSI-420 in human plasma by using HPLC with UV detection.

Zhang W, Siu LL, Moore MJ, Chen EX. Zhang W, et al. Among authors: chen ex. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jan 5;814(1):143-7. doi: 10.1016/j.jchromb.2004.10.016. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 15607718

3

Development of molecular targeted anticancer agents: successes, failures and future directions.

Chen EX, Siu LL. Chen EX, et al. Curr Pharm Des. 2005;11(2):265-72. doi: 10.2174/1381612053382205. Curr Pharm Des. 2005. PMID: 15638762 Review.

4

Imatinib mesylate in patients with adenoid cystic cancers of the salivary glands expressing c-kit: a Princess Margaret Hospital phase II consortium study.

Hotte SJ, Winquist EW, Lamont E, MacKenzie M, Vokes E, Chen EX, Brown S, Pond GR, Murgo A, Siu LL. Hotte SJ, et al. Among authors: chen ex. J Clin Oncol. 2005 Jan 20;23(3):585-90. doi: 10.1200/JCO.2005.06.125. J Clin Oncol. 2005. PMID: 15659505 Clinical Trial.

5

A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix.

Knox JJ, Siu LL, Chen E, Dimitroulakos J, Kamel-Reid S, Moore MJ, Chin S, Irish J, LaFramboise S, Oza AM. Knox JJ, et al. Eur J Cancer. 2005 Mar;41(4):523-30. doi: 10.1016/j.ejca.2004.12.013. Epub 2005 Jan 22. Eur J Cancer. 2005. PMID: 15737556 Clinical Trial.

6

Combining gemcitabine and capecitabine in patients with advanced biliary cancer: a phase II trial.

Knox JJ, Hedley D, Oza A, Feld R, Siu LL, Chen E, Nematollahi M, Pond GR, Zhang J, Moore MJ. Knox JJ, et al. J Clin Oncol. 2005 Apr 1;23(10):2332-8. doi: 10.1200/JCO.2005.51.008. J Clin Oncol. 2005. PMID: 15800324 Clinical Trial.

7

Phase I and pharmacokinetic study of Bay 38-3441, a camptothecin glycoconjugate, administered as a 30-minute infusion daily for five days every 3 weeks in patients with advanced solid malignancies.

Chen EX, Batist G, Siu LL, Bangash N, Maclean M, McIntosh L, Miller WH Jr, Oza AM, Lathia C, Petrenciuc O, Seymour L. Chen EX, et al. Invest New Drugs. 2005 Oct;23(5):455-65. doi: 10.1007/s10637-005-2905-1. Invest New Drugs. 2005. PMID: 16133797 Clinical Trial.

8

Comparison of outcomes of phase II studies and subsequent randomized control studies using identical chemotherapeutic regimens.

Zia MI, Siu LL, Pond GR, Chen EX. Zia MI, et al. Among authors: chen ex. J Clin Oncol. 2005 Oct 1;23(28):6982-91. doi: 10.1200/JCO.2005.06.679. J Clin Oncol. 2005. PMID: 16192585

9

Phase I trial of UCN-01 in combination with topotecan in patients with advanced solid cancers: a Princess Margaret Hospital Phase II Consortium study.

Hotte SJ, Oza A, Winquist EW, Moore M, Chen EX, Brown S, Pond GR, Dancey JE, Hirte HW. Hotte SJ, et al. Among authors: chen ex. Ann Oncol. 2006 Feb;17(2):334-40. doi: 10.1093/annonc/mdj076. Epub 2005 Nov 10. Ann Oncol. 2006. PMID: 16284058 Free article. Clinical Trial.

10

Phase I trial of gemcitabine, doxorubicin and cisplatin (GAP) in patients with advanced solid tumors.

Duran I, Siu LL, Chen EX, Oza AM, Sturgeon J, Chin SF, Brown S, Pond GR, Nottage M. Duran I, et al. Among authors: chen ex. Anticancer Drugs. 2006 Jan;17(1):81-7. doi: 10.1097/01.cad.0000190282.05748.63. Anticancer Drugs. 2006. PMID: 16317294 Clinical Trial.

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