Coulthard S - Search Results

1

Phase I study of MG98, an oligonucleotide antisense inhibitor of human DNA methyltransferase 1, given as a 7-day infusion in patients with advanced solid tumors.

Plummer R, Vidal L, Griffin M, Lesley M, de Bono J, Coulthard S, Sludden J, Siu LL, Chen EX, Oza AM, Reid GK, McLeod AR, Besterman JM, Lee C, Judson I, Calvert H, Boddy AV. Plummer R, et al. Among authors: coulthard s. Clin Cancer Res. 2009 May 1;15(9):3177-83. doi: 10.1158/1078-0432.CCR-08-2859. Epub 2009 Apr 21. Clin Cancer Res. 2009. PMID: 19383817 Free article. Clinical Trial.

2

Chemotherapy individualization.

Veal GJ, Coulthard SA, Boddy AV. Veal GJ, et al. Invest New Drugs. 2003 May;21(2):149-56. doi: 10.1023/a:1023517311879. Invest New Drugs. 2003. PMID: 12889736 Review.

3

The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment.

Coulthard SA, Matheson EC, Hall AG, Hogarth LA. Coulthard SA, et al. Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1385-91. doi: 10.1081/NCN-200027637. Nucleosides Nucleotides Nucleic Acids. 2004. PMID: 15571264 Review.

4

The thiopurines: an update.

Coulthard S, Hogarth L. Coulthard S, et al. Invest New Drugs. 2005 Dec;23(6):523-32. doi: 10.1007/s10637-005-4020-8. Invest New Drugs. 2005. PMID: 16267626 Review.

5

Recent advances in the pharmacogenomics of thiopurine methyltransferase.

Coulthard SA, Hall AG. Coulthard SA, et al. Pharmacogenomics J. 2001;1(4):254-61. doi: 10.1038/sj.tpj.6500066. Pharmacogenomics J. 2001. PMID: 11908768 Review.

6

The use of denaturing high-pressure liquid chromatography for the detection of mutations in thiopurine methyltransferase.

Hall AG, Hamilton P, Minto L, Coulthard SA. Hall AG, et al. Among authors: coulthard sa. J Biochem Biophys Methods. 2001 Jan 30;47(1-2):65-71. doi: 10.1016/s0165-022x(00)00152-4. J Biochem Biophys Methods. 2001. PMID: 11179762

7

The effect of thiopurine drugs on DNA methylation in relation to TPMT expression.

Hogarth LA, Redfern CP, Teodoridis JM, Hall AG, Anderson H, Case MC, Coulthard SA. Hogarth LA, et al. Among authors: coulthard sa. Biochem Pharmacol. 2008 Oct 15;76(8):1024-35. doi: 10.1016/j.bcp.2008.07.026. Epub 2008 Jul 30. Biochem Pharmacol. 2008. PMID: 18708030

8

Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines.

Zaremba T, Ketzer P, Cole M, Coulthard S, Plummer ER, Curtin NJ. Zaremba T, et al. Among authors: coulthard s. Br J Cancer. 2009 Jul 21;101(2):256-62. doi: 10.1038/sj.bjc.6605166. Epub 2009 Jun 30. Br J Cancer. 2009. PMID: 19568233 Free PMC article.

9

The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs.

Coulthard SA, Hogarth LA, Little M, Matheson EC, Redfern CP, Minto L, Hall AG. Coulthard SA, et al. Mol Pharmacol. 2002 Jul;62(1):102-9. doi: 10.1124/mol.62.1.102. Mol Pharmacol. 2002. PMID: 12065760

10

Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers.

Coulthard SA, Redfern CP, Vikingsson S, Lindqvist-Appell M, Skoglund K, Jakobsen-Falk I, Hall AG, Taylor GA, Hogarth LA. Coulthard SA, et al. Mol Cancer Ther. 2011 Mar;10(3):495-504. doi: 10.1158/1535-7163.MCT-10-0798. Epub 2011 Jan 31. Mol Cancer Ther. 2011. PMID: 21282358 Free PMC article.

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