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Neuroprotection by the NR3A subunit of the NMDA receptor.
Nakanishi N, Tu S, Shin Y, Cui J, Kurokawa T, Zhang D, Chen HS, Tong G, Lipton SA. Nakanishi N, et al. Among authors: chen hs. J Neurosci. 2009 Apr 22;29(16):5260-5. doi: 10.1523/JNEUROSCI.1067-09.2009. J Neurosci. 2009. PMID: 19386922 Free PMC article.
Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss.
Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto S, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, Sason H, Stouffer DG, Buczynski MW, Solomon JP, Michael S, Powers ET, Kelly JW, Roberts A, Tong G, Fang-Newmeyer T, Parker J, Holland EA, Zhang D, Nakanishi N, Chen HS, Wolosker H, Wang Y, Parsons LH, Ambasudhan R, Masliah E, Heinemann SF, Piña-Crespo JC, Lipton SA. Talantova M, et al. Among authors: chen hs. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2518-27. doi: 10.1073/pnas.1306832110. Epub 2013 Jun 17. Proc Natl Acad Sci U S A. 2013. PMID: 23776240 Free PMC article.
Paradigm shift in NMDA receptor drug development.
Lipton SA, Chen HS. Lipton SA, et al. Among authors: chen hs. Expert Opin Ther Targets. 2005 Jun;9(3):427-9. doi: 10.1517/14728222.9.3.427. Expert Opin Ther Targets. 2005. PMID: 15948664
The pharmacology of aminoadamantane nitrates.
Wang Y, Eu J, Washburn M, Gong T, Chen HS, James WL, Lipton SA, Stamler JS, Went GT, Porter S. Wang Y, et al. Among authors: chen hs. Curr Alzheimer Res. 2006 Jul;3(3):201-4. doi: 10.2174/156720506777632808. Curr Alzheimer Res. 2006. PMID: 16842096
1,981 results