Borchelt DR - Search Results

1

Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS.

Karch CM, Prudencio M, Winkler DD, Hart PJ, Borchelt DR. Karch CM, et al. Among authors: borchelt dr. Proc Natl Acad Sci U S A. 2009 May 12;106(19):7774-9. doi: 10.1073/pnas.0902505106. Epub 2009 Apr 30. Proc Natl Acad Sci U S A. 2009. PMID: 19416874 Free PMC article.

2

Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells.

Rabizadeh S, Gralla EB, Borchelt DR, Gwinn R, Valentine JS, Sisodia S, Wong P, Lee M, Hahn H, Bredesen DE. Rabizadeh S, et al. Among authors: borchelt dr. Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):3024-8. doi: 10.1073/pnas.92.7.3024. Proc Natl Acad Sci U S A. 1995. PMID: 7708768 Free PMC article.

3

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity.

Borchelt DR, Lee MK, Slunt HS, Guarnieri M, Xu ZS, Wong PC, Brown RH Jr, Price DL, Sisodia SS, Cleveland DW. Borchelt DR, et al. Proc Natl Acad Sci U S A. 1994 Aug 16;91(17):8292-6. doi: 10.1073/pnas.91.17.8292. Proc Natl Acad Sci U S A. 1994. PMID: 8058797 Free PMC article.

4

Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase.

Pasinelli P, Borchelt DR, Houseweart MK, Cleveland DW, Brown RH Jr. Pasinelli P, et al. Among authors: borchelt dr. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15763-8. doi: 10.1073/pnas.95.26.15763. Proc Natl Acad Sci U S A. 1998. PMID: 9861044 Free PMC article.

5

Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation.

Wang J, Xu G, Li H, Gonzales V, Fromholt D, Karch C, Copeland NG, Jenkins NA, Borchelt DR. Wang J, et al. Among authors: borchelt dr. Hum Mol Genet. 2005 Aug 15;14(16):2335-47. doi: 10.1093/hmg/ddi236. Epub 2005 Jul 6. Hum Mol Genet. 2005. PMID: 16000321

6

Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability.

Wang J, Caruano-Yzermans A, Rodriguez A, Scheurmann JP, Slunt HH, Cao X, Gitlin J, Hart PJ, Borchelt DR. Wang J, et al. Among authors: borchelt dr. J Biol Chem. 2007 Jan 5;282(1):345-52. doi: 10.1074/jbc.M604503200. Epub 2006 Nov 8. J Biol Chem. 2007. PMID: 17092942 Free PMC article.

7

A limited role for disulfide cross-linking in the aggregation of mutant SOD1 linked to familial amyotrophic lateral sclerosis.

Karch CM, Borchelt DR. Karch CM, et al. Among authors: borchelt dr. J Biol Chem. 2008 May 16;283(20):13528-37. doi: 10.1074/jbc.M800564200. Epub 2008 Mar 3. J Biol Chem. 2008. PMID: 18316367 Free PMC article.

8

Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS.

Chang Y, Kong Q, Shan X, Tian G, Ilieva H, Cleveland DW, Rothstein JD, Borchelt DR, Wong PC, Lin CL. Chang Y, et al. Among authors: borchelt dr. PLoS One. 2008 Aug 6;3(8):e2849. doi: 10.1371/journal.pone.0002849. PLoS One. 2008. PMID: 18682740 Free PMC article.

9

Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice.

Xu G, Karch C, Li N, Lin N, Fromholt D, Gonzales V, Borchelt DR. Xu G, et al. Among authors: borchelt dr. PLoS One. 2008 Sep 8;3(9):e3159. doi: 10.1371/journal.pone.0003159. PLoS One. 2008. PMID: 18776935 Free PMC article.

10

Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme.

Prudencio M, Durazo A, Whitelegge JP, Borchelt DR. Prudencio M, et al. Among authors: borchelt dr. J Neurochem. 2009 Feb;108(4):1009-18. doi: 10.1111/j.1471-4159.2008.05839.x. Epub 2008 Dec 11. J Neurochem. 2009. PMID: 19077113 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

236 results

Search Page

Filters