Martignetti JA - Search Results

1

KLF6-SV1 is a novel antiapoptotic protein that targets the BH3-only protein NOXA for degradation and whose inhibition extends survival in an ovarian cancer model.

Difeo A, Huang F, Sangodkar J, Terzo EA, Leake D, Narla G, Martignetti JA. Difeo A, et al. Among authors: martignetti ja. Cancer Res. 2009 Jun 1;69(11):4733-41. doi: 10.1158/0008-5472.CAN-08-4282. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435908 Free PMC article.

2

A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk.

Narla G, Difeo A, Reeves HL, Schaid DJ, Hirshfeld J, Hod E, Katz A, Isaacs WB, Hebbring S, Komiya A, McDonnell SK, Wiley KE, Jacobsen SJ, Isaacs SD, Walsh PC, Zheng SL, Chang BL, Friedrichsen DM, Stanford JL, Ostrander EA, Chinnaiyan AM, Rubin MA, Xu J, Thibodeau SN, Friedman SL, Martignetti JA. Narla G, et al. Among authors: martignetti ja. Cancer Res. 2005 Feb 15;65(4):1213-22. doi: 10.1158/0008-5472.CAN-04-4249. Cancer Res. 2005. PMID: 15735005

3

Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread.

Narla G, DiFeo A, Yao S, Banno A, Hod E, Reeves HL, Qiao RF, Camacho-Vanegas O, Levine A, Kirschenbaum A, Chan AM, Friedman SL, Martignetti JA. Narla G, et al. Among authors: martignetti ja. Cancer Res. 2005 Jul 1;65(13):5761-8. doi: 10.1158/0008-5472.CAN-05-0217. Cancer Res. 2005. PMID: 15994951

4

Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation.

Li D, Yea S, Dolios G, Martignetti JA, Narla G, Wang R, Walsh MJ, Friedman SL. Li D, et al. Among authors: martignetti ja. Cancer Res. 2005 Oct 15;65(20):9216-25. doi: 10.1158/0008-5472.CAN-05-1040. Cancer Res. 2005. PMID: 16230382

5

Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination.

DiFeo A, Narla G, Hirshfeld J, Camacho-Vanegas O, Narla J, Rose SL, Kalir T, Yao S, Levine A, Birrer MJ, Bonome T, Friedman SL, Buller RE, Martignetti JA. DiFeo A, et al. Among authors: martignetti ja. Clin Cancer Res. 2006 Jun 15;12(12):3730-9. doi: 10.1158/1078-0432.CCR-06-0054. Clin Cancer Res. 2006. PMID: 16778100

6

Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma.

Camacho-Vanegas O, Narla G, Teixeira MS, DiFeo A, Misra A, Singh G, Chan AM, Friedman SL, Feuerstein BG, Martignetti JA. Camacho-Vanegas O, et al. Among authors: martignetti ja. Int J Cancer. 2007 Sep 15;121(6):1390-5. doi: 10.1002/ijc.22809. Int J Cancer. 2007. PMID: 17514651

7

KLF6 allelic loss is associated with tumor recurrence and markedly decreased survival in head and neck squamous cell carcinoma.

Teixeira MS, Camacho-Vanegas O, Fernandez Y, Narla G, DiFeo A, Lee B, Kalir T, Friedman SL, Schlecht NF, Genden EM, Urken M, Brandwein-Gensler M, Martignetti JA. Teixeira MS, et al. Among authors: martignetti ja. Int J Cancer. 2007 Nov 1;121(9):1976-1983. doi: 10.1002/ijc.22926. Int J Cancer. 2007. PMID: 17621627

8

A functional role for KLF6-SV1 in lung adenocarcinoma prognosis and chemotherapy response.

DiFeo A, Feld L, Rodriguez E, Wang C, Beer DG, Martignetti JA, Narla G. DiFeo A, et al. Among authors: martignetti ja. Cancer Res. 2008 Feb 15;68(4):965-70. doi: 10.1158/0008-5472.CAN-07-2604. Epub 2008 Feb 4. Cancer Res. 2008. PMID: 18250346 Free PMC article.

9

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.

Narla G, DiFeo A, Fernandez Y, Dhanasekaran S, Huang F, Sangodkar J, Hod E, Leake D, Friedman SL, Hall SJ, Chinnaiyan AM, Gerald WL, Rubin MA, Martignetti JA. Narla G, et al. Among authors: martignetti ja. J Clin Invest. 2008 Aug;118(8):2711-21. doi: 10.1172/JCI34780. J Clin Invest. 2008. PMID: 18596922 Free PMC article.

10

The role of KLF6 and its splice variants in cancer therapy.

DiFeo A, Martignetti JA, Narla G. DiFeo A, et al. Among authors: martignetti ja. Drug Resist Updat. 2009 Feb-Apr;12(1-2):1-7. doi: 10.1016/j.drup.2008.11.001. Epub 2008 Dec 18. Drug Resist Updat. 2009. PMID: 19097929 Review.

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