He L - Search Results

1

Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein.

He L, Sabet A, Djedjos S, Miller R, Sun X, Hussain MA, Radovick S, Wondisford FE. He L, et al. Cell. 2009 May 15;137(4):635-46. doi: 10.1016/j.cell.2009.03.016. Cell. 2009. PMID: 19450513 Free PMC article.

2

CREB binding protein (CBP) activation is required for luteinizing hormone beta expression and normal fertility in mice.

Miller RS, Wolfe A, He L, Radovick S, Wondisford FE. Miller RS, et al. Among authors: he l. Mol Cell Biol. 2012 Jul;32(13):2349-58. doi: 10.1128/MCB.00394-12. Epub 2012 Apr 16. Mol Cell Biol. 2012. PMID: 22508984 Free PMC article.

3

Transcriptional co-activator p300 maintains basal hepatic gluconeogenesis.

He L, Naik K, Meng S, Cao J, Sidhaye AR, Ma A, Radovick S, Wondisford FE. He L, et al. J Biol Chem. 2012 Sep 14;287(38):32069-77. doi: 10.1074/jbc.M112.385864. Epub 2012 Jul 19. J Biol Chem. 2012. PMID: 22815486 Free PMC article.

4

Insulin-like growth factor 1 mediates negative feedback to somatotroph GH expression via POU1F1/CREB binding protein interactions.

Romero CJ, Pine-Twaddell E, Sima DI, Miller RS, He L, Wondisford F, Radovick S. Romero CJ, et al. Among authors: he l. Mol Cell Biol. 2012 Nov;32(21):4258-69. doi: 10.1128/MCB.00171-12. Epub 2012 Aug 13. Mol Cell Biol. 2012. PMID: 22890843 Free PMC article.

5

Activation of basal gluconeogenesis by coactivator p300 maintains hepatic glycogen storage.

He L, Cao J, Meng S, Ma A, Radovick S, Wondisford FE. He L, et al. Mol Endocrinol. 2013 Aug;27(8):1322-32. doi: 10.1210/me.2012-1413. Epub 2013 Jun 14. Mol Endocrinol. 2013. PMID: 23770612 Free PMC article.

6

Potential biomarker of metformin action.

He L, Meng S, Germain-Lee EL, Radovick S, Wondisford FE. He L, et al. J Endocrinol. 2014 Jun;221(3):363-9. doi: 10.1530/JOE-14-0084. Epub 2014 Mar 17. J Endocrinol. 2014. PMID: 24639469 Free PMC article.

7

Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK).

Cao J, Meng S, Chang E, Beckwith-Fickas K, Xiong L, Cole RN, Radovick S, Wondisford FE, He L. Cao J, et al. Among authors: he l. J Biol Chem. 2014 Jul 25;289(30):20435-46. doi: 10.1074/jbc.M114.567271. J Biol Chem. 2014. PMID: 24928508 Free PMC article.

8

Metformin activates AMP-activated protein kinase by promoting formation of the αβγ heterotrimeric complex.

Meng S, Cao J, He Q, Xiong L, Chang E, Radovick S, Wondisford FE, He L. Meng S, et al. Among authors: he l, he q. J Biol Chem. 2015 Feb 6;290(6):3793-802. doi: 10.1074/jbc.M114.604421. Epub 2014 Dec 23. J Biol Chem. 2015. PMID: 25538235 Free PMC article.

9

Metformin action: concentrations matter.

He L, Wondisford FE. He L, et al. Cell Metab. 2015 Feb 3;21(2):159-162. doi: 10.1016/j.cmet.2015.01.003. Cell Metab. 2015. PMID: 25651170 Free article.

10

Metformin Acts on Two Different Molecular Pathways to Enhance Adult Neural Precursor Proliferation/Self-Renewal and Differentiation.

Fatt M, Hsu K, He L, Wondisford F, Miller FD, Kaplan DR, Wang J. Fatt M, et al. Among authors: he l. Stem Cell Reports. 2015 Dec 8;5(6):988-995. doi: 10.1016/j.stemcr.2015.10.014. Epub 2015 Nov 19. Stem Cell Reports. 2015. PMID: 26677765 Free PMC article.

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