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EPS8 and E3B1 transduce signals from Ras to Rac.
Scita G, Nordstrom J, Carbone R, Tenca P, Giardina G, Gutkind S, Bjarnegård M, Betsholtz C, Di Fiore PP. Scita G, et al. Among authors: di fiore pp. Nature. 1999 Sep 16;401(6750):290-3. doi: 10.1038/45822. Nature. 1999. PMID: 10499589
Signaling from Ras to Rac and beyond: not just a matter of GEFs.
Scita G, Tenca P, Frittoli E, Tocchetti A, Innocenti M, Giardina G, Di Fiore PP. Scita G, et al. Among authors: di fiore pp. EMBO J. 2000 Jun 1;19(11):2393-8. doi: 10.1093/emboj/19.11.2393. EMBO J. 2000. PMID: 10835338 Free PMC article. Review.
An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine.
Scita G, Tenca P, Areces LB, Tocchetti A, Frittoli E, Giardina G, Ponzanelli I, Sini P, Innocenti M, Di Fiore PP. Scita G, et al. Among authors: di fiore pp. J Cell Biol. 2001 Sep 3;154(5):1031-44. doi: 10.1083/jcb.200103146. Epub 2001 Aug 27. J Cell Biol. 2001. PMID: 11524436 Free PMC article.
Mechanisms through which Sos-1 coordinates the activation of Ras and Rac.
Innocenti M, Tenca P, Frittoli E, Faretta M, Tocchetti A, Di Fiore PP, Scita G. Innocenti M, et al. Among authors: di fiore pp. J Cell Biol. 2002 Jan 7;156(1):125-36. doi: 10.1083/jcb.200108035. Epub 2002 Jan 3. J Cell Biol. 2002. PMID: 11777939 Free PMC article.
Eps8 in the midst of GTPases.
Di Fiore PP, Scita G. Di Fiore PP, et al. Int J Biochem Cell Biol. 2002 Oct;34(10):1178-83. doi: 10.1016/s1357-2725(02)00064-x. Int J Biochem Cell Biol. 2002. PMID: 12127568 Review.
293 results