Duque-Afonso J - Search Results

1

Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes.

Hauswald S, Duque-Afonso J, Wagner MM, Schertl FM, Lübbert M, Peschel C, Keller U, Licht T. Hauswald S, et al. Clin Cancer Res. 2009 Jun 1;15(11):3705-15. doi: 10.1158/1078-0432.CCR-08-2048. Epub 2009 May 19. Clin Cancer Res. 2009. PMID: 19458058

2

Long-term complete remission of refractory severe idiopathic immune thrombocytopenia (ITP) treated with daratumumab.

Strüßmann T, Jung J, Heinz J, Duque Afonso J, Wäsch R, Engelhardt M, Duyster J, Finke J, Marks R. Strüßmann T, et al. Ann Hematol. 2023 Jan;102(1):245-247. doi: 10.1007/s00277-022-05035-y. Epub 2022 Nov 17. Ann Hematol. 2023. PMID: 36394581 Free PMC article. No abstract available.

3

XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from molecular pathogenesis to targeted therapy in leukemia and solid tumors.

Hackanson B, Becker H, Berg T, Binder M, Dierks C, Duque-Afonso J, Lairmore MD, Schäfer HS, Schnitzler M, Zeiser R, Martens U, Mertelsmann R, Lübbert M. Hackanson B, et al. Cancer Res. 2008 Jul 15;68(14):5512-8. doi: 10.1158/0008-5472.CAN-07-6859. Cancer Res. 2008. PMID: 18632600 Free PMC article. No abstract available.

4

The DNA demethylating agent 5-aza-2'-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells.

Almstedt M, Blagitko-Dorfs N, Duque-Afonso J, Karbach J, Pfeifer D, Jäger E, Lübbert M. Almstedt M, et al. Leuk Res. 2010 Jul;34(7):899-905. doi: 10.1016/j.leukres.2010.02.004. Epub 2010 Apr 10. Leuk Res. 2010. PMID: 20381863

5

Regulation of the adaptor molecule LAT2, an in vivo target gene of AML1/ETO (RUNX1/RUNX1T1), during myeloid differentiation.

Duque-Afonso J, Solari L, Essig A, Berg T, Pahl HL, Lübbert M. Duque-Afonso J, et al. Br J Haematol. 2011 Jun;153(5):612-22. doi: 10.1111/j.1365-2141.2011.08586.x. Epub 2011 Apr 13. Br J Haematol. 2011. PMID: 21488857 Free article.

6

The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO.

Duque-Afonso J, Yalcin A, Berg T, Abdelkarim M, Heidenreich O, Lübbert M. Duque-Afonso J, et al. Oncogene. 2011 Jul 7;30(27):3062-72. doi: 10.1038/onc.2011.32. Epub 2011 May 16. Oncogene. 2011. PMID: 21577204

7

Epigenetic priming of AML blasts for all-trans retinoic acid-induced differentiation by the HDAC class-I selective inhibitor entinostat.

Blagitko-Dorfs N, Jiang Y, Duque-Afonso J, Hiller J, Yalcin A, Greve G, Abdelkarim M, Hackanson B, Lübbert M. Blagitko-Dorfs N, et al. PLoS One. 2013 Oct 8;8(10):e75258. doi: 10.1371/journal.pone.0075258. eCollection 2013. PLoS One. 2013. PMID: 24116031 Free PMC article.

8

The AML1/ETO target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells.

Essig A, Duque-Afonso J, Schwemmers S, Pahl HL, Lübbert M. Essig A, et al. Leuk Res. 2014 Mar;38(3):340-5. doi: 10.1016/j.leukres.2013.12.014. Epub 2013 Dec 25. Leuk Res. 2014. PMID: 24456692 Free PMC article.

9

Identification of enhancer of mRNA decapping 4 as a novel fusion partner of MLL in acute myeloid leukemia.

Becker H, Greve G, Kataoka K, Mallm JP, Duque-Afonso J, Ma T, Niemöller C, Pantic M, Duyster J, Cleary ML, Schüler J, Rippe K, Ogawa S, Lübbert M. Becker H, et al. Blood Adv. 2019 Mar 12;3(5):761-765. doi: 10.1182/bloodadvances.2018023879. Blood Adv. 2019. PMID: 30833276 Free PMC article.

10

The epigenetics of breast cancer - Opportunities for diagnostics, risk stratification and therapy.

Schröder R, Illert AL, Erbes T, Flotho C, Lübbert M, Duque-Afonso J. Schröder R, et al. Epigenetics. 2022 Jun;17(6):612-624. doi: 10.1080/15592294.2021.1940644. Epub 2021 Jun 23. Epigenetics. 2022. PMID: 34159881 Free PMC article.

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