Fisher RP - Search Results

1

Behind the wheel and under the hood: functions of cyclin-dependent kinases in response to DNA damage.

Wohlbold L, Fisher RP. Wohlbold L, et al. Among authors: fisher rp. DNA Repair (Amst). 2009 Sep 2;8(9):1018-24. doi: 10.1016/j.dnarep.2009.04.009. Epub 2009 May 22. DNA Repair (Amst). 2009. PMID: 19464967 Free PMC article. Review.

2

CDK-activating kinases: detection and activity measurements.

Larochelle S, Fisher RP. Larochelle S, et al. Among authors: fisher rp. Methods Mol Biol. 2005;296:279-90. doi: 10.1385/1-59259-857-9:279. Methods Mol Biol. 2005. PMID: 15576939

3

The cyclin-dependent kinase (CDK) family member PNQALRE/CCRK supports cell proliferation but has no intrinsic CDK-activating kinase (CAK) activity.

Wohlbold L, Larochelle S, Liao JC, Livshits G, Singer J, Shokat KM, Fisher RP. Wohlbold L, et al. Among authors: fisher rp. Cell Cycle. 2006 Mar;5(5):546-54. doi: 10.4161/cc.5.5.2541. Epub 2006 Mar 1. Cell Cycle. 2006. PMID: 16552187

4

Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.

Larochelle S, Merrick KA, Terret ME, Wohlbold L, Barboza NM, Zhang C, Shokat KM, Jallepalli PV, Fisher RP. Larochelle S, et al. Among authors: fisher rp. Mol Cell. 2007 Mar 23;25(6):839-50. doi: 10.1016/j.molcel.2007.02.003. Mol Cell. 2007. PMID: 17386261 Free PMC article.

5

Distinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cells.

Merrick KA, Larochelle S, Zhang C, Allen JJ, Shokat KM, Fisher RP. Merrick KA, et al. Among authors: fisher rp. Mol Cell. 2008 Dec 5;32(5):662-72. doi: 10.1016/j.molcel.2008.10.022. Mol Cell. 2008. PMID: 19061641 Free PMC article.

6

Coming full circle: cyclin-dependent kinases as anti-cancer drug targets.

Fisher RP. Fisher RP. Subcell Biochem. 2010;50:1-15. doi: 10.1007/978-90-481-3471-7_1. Subcell Biochem. 2010. PMID: 20012574 Review.

7

Putting one step before the other: distinct activation pathways for Cdk1 and Cdk2 bring order to the mammalian cell cycle.

Merrick KA, Fisher RP. Merrick KA, et al. Among authors: fisher rp. Cell Cycle. 2010 Feb 15;9(4):706-14. doi: 10.4161/cc.9.4.10732. Epub 2010 Feb 23. Cell Cycle. 2010. PMID: 20139727 Free PMC article.

8

Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation.

Merrick KA, Wohlbold L, Zhang C, Allen JJ, Horiuchi D, Huskey NE, Goga A, Shokat KM, Fisher RP. Merrick KA, et al. Among authors: fisher rp. Mol Cell. 2011 Jun 10;42(5):624-36. doi: 10.1016/j.molcel.2011.03.031. Mol Cell. 2011. PMID: 21658603 Free PMC article.

9

Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways.

Horiuchi D, Huskey NE, Kusdra L, Wohlbold L, Merrick KA, Zhang C, Creasman KJ, Shokat KM, Fisher RP, Goga A. Horiuchi D, et al. Among authors: fisher rp. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):E1019-27. doi: 10.1073/pnas.1111317109. Epub 2012 Apr 3. Proc Natl Acad Sci U S A. 2012. PMID: 22474407 Free PMC article.

10

Why minimal is not optimal: driving the mammalian cell cycle--and drug discovery--with a physiologic CDK control network.

Merrick KA, Fisher RP. Merrick KA, et al. Among authors: fisher rp. Cell Cycle. 2012 Jul 15;11(14):2600-5. doi: 10.4161/cc.20758. Epub 2012 Jul 15. Cell Cycle. 2012. PMID: 22732498 Free PMC article.

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