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Page 1
Buffer optimization of thermal melt assays of Plasmodium proteins for detection of small-molecule ligands.
Crowther GJ, Napuli AJ, Thomas AP, Chung DJ, Kovzun KV, Leibly DJ, Castaneda LJ, Bhandari J, Damman CJ, Hui R, Hol WG, Buckner FS, Verlinde CL, Zhang Z, Fan E, van Voorhis WC. Crowther GJ, et al. Among authors: leibly dj. J Biomol Screen. 2009 Jul;14(6):700-7. doi: 10.1177/1087057109335749. Epub 2009 May 21. J Biomol Screen. 2009. PMID: 19470714 Free PMC article.
Use of thermal melt curves to assess the quality of enzyme preparations.
Crowther GJ, He P, Rodenbough PP, Thomas AP, Kovzun KV, Leibly DJ, Bhandari J, Castaneda LJ, Hol WG, Gelb MH, Napuli AJ, Van Voorhis WC. Crowther GJ, et al. Among authors: leibly dj. Anal Biochem. 2010 Apr 15;399(2):268-75. doi: 10.1016/j.ab.2009.12.018. Epub 2009 Dec 14. Anal Biochem. 2010. PMID: 20018159 Free PMC article.
Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds.
Crowther GJ, Napuli AJ, Gilligan JH, Gagaring K, Borboa R, Francek C, Chen Z, Dagostino EF, Stockmyer JB, Wang Y, Rodenbough PP, Castaneda LJ, Leibly DJ, Bhandari J, Gelb MH, Brinker A, Engels IH, Taylor J, Chatterjee AK, Fantauzzi P, Glynne RJ, Van Voorhis WC, Kuhen KL. Crowther GJ, et al. Among authors: leibly dj. Mol Biochem Parasitol. 2011 Jan;175(1):21-9. doi: 10.1016/j.molbiopara.2010.08.005. Epub 2010 Sep 15. Mol Biochem Parasitol. 2011. PMID: 20813141 Free PMC article.
Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1.
Larson ET, Ojo KK, Murphy RC, Johnson SM, Zhang Z, Kim JE, Leibly DJ, Fox AM, Reid MC, Dale EJ, Perera BG, Kim J, Hewitt SN, Hol WG, Verlinde CL, Fan E, Van Voorhis WC, Maly DJ, Merritt EA. Larson ET, et al. Among authors: leibly dj. J Med Chem. 2012 Mar 22;55(6):2803-10. doi: 10.1021/jm201725v. Epub 2012 Mar 13. J Med Chem. 2012. PMID: 22369268 Free PMC article.
Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors.
Ojo KK, Pfander C, Mueller NR, Burstroem C, Larson ET, Bryan CM, Fox AM, Reid MC, Johnson SM, Murphy RC, Kennedy M, Mann H, Leibly DJ, Hewitt SN, Verlinde CL, Kappe S, Merritt EA, Maly DJ, Billker O, Van Voorhis WC. Ojo KK, et al. Among authors: leibly dj. J Clin Invest. 2012 Jun;122(6):2301-5. doi: 10.1172/JCI61822. Epub 2012 May 8. J Clin Invest. 2012. PMID: 22565309 Free PMC article.
High-throughput protein production and purification at the Seattle Structural Genomics Center for Infectious Disease.
Bryan CM, Bhandari J, Napuli AJ, Leibly DJ, Choi R, Kelley A, Van Voorhis WC, Edwards TE, Stewart LJ. Bryan CM, et al. Among authors: leibly dj. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):1010-4. doi: 10.1107/S1744309111018367. Epub 2011 Aug 13. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21904042 Free PMC article.
Structures of phosphopantetheine adenylyltransferase from Burkholderia pseudomallei.
Edwards TE, Leibly DJ, Bhandari J, Statnekov JB, Phan I, Dieterich SH, Abendroth J, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Edwards TE, et al. Among authors: leibly dj. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):1032-7. doi: 10.1107/S1744309111004349. Epub 2011 Aug 13. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21904046 Free PMC article.
Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head.
Edwards TE, Phan I, Abendroth J, Dieterich SH, Masoudi A, Guo W, Hewitt SN, Kelley A, Leibly D, Brittnacher MJ, Staker BL, Miller SI, Van Voorhis WC, Myler PJ, Stewart LJ. Edwards TE, et al. PLoS One. 2010 Sep 20;5(9):e12803. doi: 10.1371/journal.pone.0012803. PLoS One. 2010. PMID: 20862217 Free PMC article.
20 results