Fitzpatrick PF - Search Results

1

Spectroscopy and kinetics of wild-type and mutant tyrosine hydroxylase: mechanistic insight into O2 activation.

Chow MS, Eser BE, Wilson SA, Hodgson KO, Hedman B, Fitzpatrick PF, Solomon EI. Chow MS, et al. Among authors: fitzpatrick pf. J Am Chem Soc. 2009 Jun 10;131(22):7685-98. doi: 10.1021/ja810080c. J Am Chem Soc. 2009. PMID: 19489646 Free PMC article.

2

Crystal structure of tyrosine hydroxylase at 2.3 A and its implications for inherited neurodegenerative diseases.

Goodwill KE, Sabatier C, Marks C, Raag R, Fitzpatrick PF, Stevens RC. Goodwill KE, et al. Among authors: fitzpatrick pf. Nat Struct Biol. 1997 Jul;4(7):578-85. doi: 10.1038/nsb0797-578. Nat Struct Biol. 1997. PMID: 9228951

3

Effects of phosphorylation on binding of catecholamines to tyrosine hydroxylase: specificity and thermodynamics.

Ramsey AJ, Fitzpatrick PF. Ramsey AJ, et al. Among authors: fitzpatrick pf. Biochemistry. 2000 Feb 1;39(4):773-8. doi: 10.1021/bi991901r. Biochemistry. 2000. PMID: 10651643

4

Intrinsic deuterium isotope effects on benzylic hydroxylation by tyrosine hydroxylase.

Frantom PA, Pongdee R, Sulikowski GA, Fitzpatrick PF. Frantom PA, et al. Among authors: fitzpatrick pf. J Am Chem Soc. 2002 Apr 24;124(16):4202-3. doi: 10.1021/ja025602s. J Am Chem Soc. 2002. PMID: 11960436

5

Uncoupled forms of tyrosine hydroxylase unmask kinetic isotope effects on chemical steps.

Frantom PA, Fitzpatrick PF. Frantom PA, et al. Among authors: fitzpatrick pf. J Am Chem Soc. 2003 Dec 31;125(52):16190-1. doi: 10.1021/ja0383165. J Am Chem Soc. 2003. PMID: 14692751 Free PMC article.

6

Direct spectroscopic evidence for a high-spin Fe(IV) intermediate in tyrosine hydroxylase.

Eser BE, Barr EW, Frantom PA, Saleh L, Bollinger JM Jr, Krebs C, Fitzpatrick PF. Eser BE, et al. Among authors: fitzpatrick pf. J Am Chem Soc. 2007 Sep 19;129(37):11334-5. doi: 10.1021/ja074446s. Epub 2007 Aug 23. J Am Chem Soc. 2007. PMID: 17715926 Free PMC article. No abstract available.

7

Demonstration of a peroxide shunt in the tetrahydropterin-dependent aromatic amino acid monooxygenases.

Pavon JA, Fitzpatrick PF. Pavon JA, et al. Among authors: fitzpatrick pf. J Am Chem Soc. 2009 Apr 8;131(13):4582-3. doi: 10.1021/ja900128m. J Am Chem Soc. 2009. PMID: 19281164 Free PMC article.

8

Measurement of intrinsic rate constants in the tyrosine hydroxylase reaction.

Eser BE, Fitzpatrick PF. Eser BE, et al. Among authors: fitzpatrick pf. Biochemistry. 2010 Jan 26;49(3):645-52. doi: 10.1021/bi901874e. Biochemistry. 2010. PMID: 20025246 Free PMC article.

9

Single turnover kinetics of tryptophan hydroxylase: evidence for a new intermediate in the reaction of the aromatic amino acid hydroxylases.

Pavon JA, Eser B, Huynh MT, Fitzpatrick PF. Pavon JA, et al. Among authors: fitzpatrick pf. Biochemistry. 2010 Sep 7;49(35):7563-71. doi: 10.1021/bi100744r. Biochemistry. 2010. PMID: 20687613 Free PMC article.

10

Pulsed EPR study of amino acid and tetrahydropterin binding in a tyrosine hydroxylase nitric oxide complex: evidence for substrate rearrangements in the formation of the oxygen-reactive complex.

Krzyaniak MD, Eser BE, Ellis HR, Fitzpatrick PF, McCracken J. Krzyaniak MD, et al. Among authors: fitzpatrick pf. Biochemistry. 2013 Nov 26;52(47):8430-41. doi: 10.1021/bi4010914. Epub 2013 Nov 14. Biochemistry. 2013. PMID: 24168553 Free PMC article.

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