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Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata.
Salát J, Paesen GC, Rezácová P, Kotsyfakis M, Kovárová Z, Sanda M, Majtán J, Grunclová L, Horká H, Andersen JF, Brynda J, Horn M, Nunn MA, Kopácek P, Kopecký J, Mares M. Salát J, et al. Among authors: kotsyfakis m. Biochem J. 2010 Jul 1;429(1):103-12. doi: 10.1042/BJ20100280. Biochem J. 2010. PMID: 20545626 Free PMC article.
Cysteine proteases from bloodfeeding arthropod ectoparasites.
Sojka D, Francischetti IM, Calvo E, Kotsyfakis M. Sojka D, et al. Among authors: kotsyfakis m. Adv Exp Med Biol. 2011;712:177-91. doi: 10.1007/978-1-4419-8414-2_11. Adv Exp Med Biol. 2011. PMID: 21660665 Free PMC article. Review.
The tick salivary protein sialostatin L inhibits the Th9-derived production of the asthma-promoting cytokine IL-9 and is effective in the prevention of experimental asthma.
Horka H, Staudt V, Klein M, Taube C, Reuter S, Dehzad N, Andersen JF, Kopecky J, Schild H, Kotsyfakis M, Hoffmann M, Gerlitzki B, Stassen M, Bopp T, Schmitt E. Horka H, et al. Among authors: kotsyfakis m. J Immunol. 2012 Mar 15;188(6):2669-76. doi: 10.4049/jimmunol.1100529. Epub 2012 Feb 10. J Immunol. 2012. PMID: 22327077 Free PMC article.
Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo.
Collin N, Assumpção TC, Mizurini DM, Gilmore DC, Dutra-Oliveira A, Kotsyfakis M, Sá-Nunes A, Teixeira C, Ribeiro JM, Monteiro RQ, Valenzuela JG, Francischetti IM. Collin N, et al. Among authors: kotsyfakis m. Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2185-98. doi: 10.1161/ATVBAHA.112.253906. Epub 2012 Jul 12. Arterioscler Thromb Vasc Biol. 2012. PMID: 22796577 Free PMC article.
95 results