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Page 1
Metamorphic enzyme assembly in polyketide diversification.
Gu L, Wang B, Kulkarni A, Geders TW, Grindberg RV, Gerwick L, Håkansson K, Wipf P, Smith JL, Gerwick WH, Sherman DH. Gu L, et al. Among authors: wipf p. Nature. 2009 Jun 4;459(7247):731-5. doi: 10.1038/nature07870. Nature. 2009. PMID: 19494914 Free PMC article.
Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase.
Gehret JJ, Gu L, Gerwick WH, Wipf P, Sherman DH, Smith JL. Gehret JJ, et al. Among authors: wipf p. J Biol Chem. 2011 Apr 22;286(16):14445-54. doi: 10.1074/jbc.M110.214635. Epub 2011 Feb 27. J Biol Chem. 2011. PMID: 21357626 Free PMC article.
J., Lloyd, K. R., Gerwick, L., Gerwick, W. H., Wipf, P., Hakansson, K., Smith, J. L., and Sherman, D. H. (2009) J. Am. Chem. Soc. 131, 16033-16035). ...
J., Lloyd, K. R., Gerwick, L., Gerwick, W. H., Wipf, P., Hakansson, K., Smith, J. L., and Sherman, D. H. (2009) J. Am. Chem. S …
Structural Basis of Polyketide Synthase O-Methylation.
Skiba MA, Bivins MM, Schultz JR, Bernard SM, Fiers WD, Dan Q, Kulkarni S, Wipf P, Gerwick WH, Sherman DH, Aldrich CC, Smith JL. Skiba MA, et al. Among authors: wipf p. ACS Chem Biol. 2018 Dec 21;13(12):3221-3228. doi: 10.1021/acschembio.8b00687. Epub 2018 Dec 3. ACS Chem Biol. 2018. PMID: 30489068 Free PMC article.
Click chemistry: Straining to react.
Milligan JA, Wipf P. Milligan JA, et al. Among authors: wipf p. Nat Chem. 2016 Apr;8(4):296-7. doi: 10.1038/nchem.2485. Nat Chem. 2016. PMID: 27001724 No abstract available.
Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells.
Chokshi CR, Shaikh MV, Brakel B, Rossotti MA, Tieu D, Maich W, Anand A, Chafe SC, Zhai K, Suk Y, Kieliszek AM, Miletic P, Mikolajewicz N, Chen D, McNicol JD, Chan K, Tong AHY, Kuhlmann L, Liu L, Alizada Z, Mobilio D, Tatari N, Savage N, Aghaei N, Grewal S, Puri A, Subapanditha M, McKenna D, Ignatchenko V, Salamoun JM, Kwiecien JM, Wipf P, Sharlow ER, Provias JP, Lu JQ, Lazo JS, Kislinger T, Lu Y, Brown KR, Venugopal C, Henry KA, Moffat J, Singh SK. Chokshi CR, et al. Among authors: wipf p. Nat Med. 2024 Oct;30(10):2936-2946. doi: 10.1038/s41591-024-03138-9. Epub 2024 Aug 2. Nat Med. 2024. PMID: 39095594
Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer.
Rodina A, Vilenchik M, Moulick K, Aguirre J, Kim J, Chiang A, Litz J, Clement CC, Kang Y, She Y, Wu N, Felts S, Wipf P, Massague J, Jiang X, Brodsky JL, Krystal GW, Chiosis G. Rodina A, et al. Among authors: wipf p. Nat Chem Biol. 2007 Aug;3(8):498-507. doi: 10.1038/nchembio.2007.10. Epub 2007 Jul 1. Nat Chem Biol. 2007. PMID: 17603540
461 results