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Rutin from Lonicera japonica inhibits myocardial ischemia/reperfusion-induced apoptosis in vivo and protects H9c2 cells against hydrogen peroxide-mediated injury via ERK1/2 and PI3K/Akt signals in vitro.
Jeong JJ, Ha YM, Jin YC, Lee EJ, Kim JS, Kim HJ, Seo HG, Lee JH, Kang SS, Kim YS, Chang KC. Jeong JJ, et al. Among authors: lee ej, lee jh. Food Chem Toxicol. 2009 Jul;47(7):1569-76. doi: 10.1016/j.fct.2009.03.044. Epub 2009 Apr 9. Food Chem Toxicol. 2009. PMID: 19362115
(S)-1-(alpha-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD712) reduces rat myocardial apoptosis against ischemia and reperfusion injury by activation of phosphatidylinositol 3-kinase/Akt signaling and anti-inflammatory action in vivo.
Jin YC, Lee YS, Kim YM, Seo HG, Lee JH, Kim HJ, Yun-Choi HS, Chang KC. Jin YC, et al. Among authors: lee ys, lee jh. J Pharmacol Exp Ther. 2009 Aug;330(2):440-8. doi: 10.1124/jpet.108.150342. Epub 2009 May 20. J Pharmacol Exp Ther. 2009. PMID: 19458286
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