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Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates.
Larsen MH, Biermann K, Chen B, Hsu T, Sambandamurthy VK, Lackner AA, Aye PP, Didier P, Huang D, Shao L, Wei H, Letvin NL, Frothingham R, Haynes BF, Chen ZW, Jacobs WR Jr. Larsen MH, et al. Among authors: chen b, chen zw. Vaccine. 2009 Jul 23;27(34):4709-17. doi: 10.1016/j.vaccine.2009.05.050. Epub 2009 Jun 2. Vaccine. 2009. PMID: 19500524 Free PMC article.
Immunization of Vγ2Vδ2 T cells programs sustained effector memory responses that control tuberculosis in nonhuman primates.
Shen L, Frencher J, Huang D, Wang W, Yang E, Chen CY, Zhang Z, Wang R, Qaqish A, Larsen MH, Shen H, Porcelli SA, Jacobs WR Jr, Chen ZW. Shen L, et al. Among authors: chen cy, chen zw. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6371-6378. doi: 10.1073/pnas.1811380116. Epub 2019 Mar 8. Proc Natl Acad Sci U S A. 2019. PMID: 30850538 Free PMC article.
Immune distribution and localization of phosphoantigen-specific Vgamma2Vdelta2 T cells in lymphoid and nonlymphoid tissues in Mycobacterium tuberculosis infection.
Huang D, Shen Y, Qiu L, Chen CY, Shen L, Estep J, Hunt R, Vasconcelos D, Du G, Aye P, Lackner AA, Larsen MH, Jacobs WR Jr, Haynes BF, Letvin NL, Chen ZW. Huang D, et al. Among authors: chen cy, chen zw. Infect Immun. 2008 Jan;76(1):426-36. doi: 10.1128/IAI.01008-07. Epub 2007 Oct 8. Infect Immun. 2008. PMID: 17923514 Free PMC article.
A critical role for CD8 T cells in a nonhuman primate model of tuberculosis.
Chen CY, Huang D, Wang RC, Shen L, Zeng G, Yao S, Shen Y, Halliday L, Fortman J, McAllister M, Estep J, Hunt R, Vasconcelos D, Du G, Porcelli SA, Larsen MH, Jacobs WR Jr, Haynes BF, Letvin NL, Chen ZW. Chen CY, et al. Among authors: chen zw. PLoS Pathog. 2009 Apr;5(4):e1000392. doi: 10.1371/journal.ppat.1000392. Epub 2009 Apr 17. PLoS Pathog. 2009. PMID: 19381260 Free PMC article.
Intranasal vaccination with the recombinant Listeria monocytogenes ΔactA prfA* mutant elicits robust systemic and pulmonary cellular responses and secretory mucosal IgA.
Qiu J, Yan L, Chen J, Chen CY, Shen L, Letvin NL, Haynes BF, Freitag N, Rong L, Frencher JT, Huang D, Wang X, Chen ZW. Qiu J, et al. Among authors: chen j, chen cy, chen zw. Clin Vaccine Immunol. 2011 Apr;18(4):640-6. doi: 10.1128/CVI.00254-10. Epub 2011 Jan 26. Clin Vaccine Immunol. 2011. PMID: 21270282 Free PMC article.
Severe tuberculosis induces unbalanced up-regulation of gene networks and overexpression of IL-22, MIP-1alpha, CCL27, IP-10, CCR4, CCR5, CXCR3, PD1, PDL2, IL-3, IFN-beta, TIM1, and TLR2 but low antigen-specific cellular responses.
Qiu L, Huang D, Chen CY, Wang R, Shen L, Shen Y, Hunt R, Estep J, Haynes BF, Jacobs WR Jr, Letvin N, Du G, Chen ZW. Qiu L, et al. Among authors: chen cy, chen zw. J Infect Dis. 2008 Nov 15;198(10):1514-9. doi: 10.1086/592448. J Infect Dis. 2008. PMID: 18811584 Free PMC article.
952 results