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Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates.
Larsen MH, Biermann K, Chen B, Hsu T, Sambandamurthy VK, Lackner AA, Aye PP, Didier P, Huang D, Shao L, Wei H, Letvin NL, Frothingham R, Haynes BF, Chen ZW, Jacobs WR Jr. Larsen MH, et al. Among authors: lackner aa. Vaccine. 2009 Jul 23;27(34):4709-17. doi: 10.1016/j.vaccine.2009.05.050. Epub 2009 Jun 2. Vaccine. 2009. PMID: 19500524 Free PMC article.
Immune distribution and localization of phosphoantigen-specific Vgamma2Vdelta2 T cells in lymphoid and nonlymphoid tissues in Mycobacterium tuberculosis infection.
Huang D, Shen Y, Qiu L, Chen CY, Shen L, Estep J, Hunt R, Vasconcelos D, Du G, Aye P, Lackner AA, Larsen MH, Jacobs WR Jr, Haynes BF, Letvin NL, Chen ZW. Huang D, et al. Among authors: lackner aa. Infect Immun. 2008 Jan;76(1):426-36. doi: 10.1128/IAI.01008-07. Epub 2007 Oct 8. Infect Immun. 2008. PMID: 17923514 Free PMC article.
The non-human primate model of tuberculosis.
Kaushal D, Mehra S, Didier PJ, Lackner AA. Kaushal D, et al. Among authors: lackner aa. J Med Primatol. 2012 Jun;41(3):191-201. doi: 10.1111/j.1600-0684.2012.00536.x. Epub 2012 Mar 20. J Med Primatol. 2012. PMID: 22429048 Free PMC article. Review.
CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection.
Foreman TW, Mehra S, LoBato DN, Malek A, Alvarez X, Golden NA, Bucşan AN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Roy CJ, Blanchard J, Kuroda MJ, Lackner AA, Chan J, Khader SA, Jacobs WR Jr, Kaushal D. Foreman TW, et al. Among authors: lackner aa. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5636-44. doi: 10.1073/pnas.1611987113. Epub 2016 Sep 6. Proc Natl Acad Sci U S A. 2016. PMID: 27601645 Free PMC article.
Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge.
Darrah PA, Bolton DL, Lackner AA, Kaushal D, Aye PP, Mehra S, Blanchard JL, Didier PJ, Roy CJ, Rao SS, Hokey DA, Scanga CA, Sizemore DR, Sadoff JC, Roederer M, Seder RA. Darrah PA, et al. Among authors: lackner aa. J Immunol. 2014 Aug 15;193(4):1799-811. doi: 10.4049/jimmunol.1400676. Epub 2014 Jul 14. J Immunol. 2014. PMID: 25024382 Free PMC article.
Rabies virus-based vaccines elicit neutralizing antibodies, poly-functional CD8+ T cell, and protect rhesus macaques from AIDS-like disease after SIV(mac251) challenge.
Faul EJ, Aye PP, Papaneri AB, Pahar B, McGettigan JP, Schiro F, Chervoneva I, Montefiori DC, Lackner AA, Schnell MJ. Faul EJ, et al. Among authors: lackner aa. Vaccine. 2009 Dec 11;28(2):299-308. doi: 10.1016/j.vaccine.2009.10.051. Epub 2009 Oct 29. Vaccine. 2009. PMID: 19879223 Free PMC article.
Nonpathologic Infection of Macaques by an Attenuated Mycobacterial Vaccine Is Not Reactivated in the Setting of HIV Co-Infection.
Foreman TW, Veatch AV, LoBato DN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Lackner AA, Kousoulas KG, Khader SA, Kaushal D, Mehra S. Foreman TW, et al. Among authors: lackner aa. Am J Pathol. 2017 Dec;187(12):2811-2820. doi: 10.1016/j.ajpath.2017.08.014. Epub 2017 Sep 19. Am J Pathol. 2017. PMID: 28935575 Free PMC article.
271 results