Greene N - Search Results

1

A current practice for predicting ocular toxicity of systemically delivered drugs.

Somps CJ, Greene N, Render JA, Aleo MD, Fortner JH, Dykens JA, Phillips G. Somps CJ, et al. Among authors: greene n. Cutan Ocul Toxicol. 2009;28(1):1-18. doi: 10.1080/15569520802618585. Cutan Ocul Toxicol. 2009. PMID: 19514919 Review.

2

Computer systems for the prediction of toxicity: an update.

Greene N. Greene N. Adv Drug Deliv Rev. 2002 Mar 31;54(3):417-31. doi: 10.1016/s0169-409x(02)00012-1. Adv Drug Deliv Rev. 2002. PMID: 11922956 Review.

3

Early toxicity screening strategies.

Greene N, Naven R. Greene N, et al. Curr Opin Drug Discov Devel. 2009 Jan;12(1):90-7. Curr Opin Drug Discov Devel. 2009. PMID: 19152217

4

Developing structure-activity relationships for the prediction of hepatotoxicity.

Greene N, Fisk L, Naven RT, Note RR, Patel ML, Pelletier DJ. Greene N, et al. Chem Res Toxicol. 2010 Jul 19;23(7):1215-22. doi: 10.1021/tx1000865. Chem Res Toxicol. 2010. PMID: 20553011

5

Using an in vitro cytotoxicity assay to aid in compound selection for in vivo safety studies.

Greene N, Aleo MD, Louise-May S, Price DA, Will Y. Greene N, et al. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5308-12. doi: 10.1016/j.bmcl.2010.06.129. Epub 2010 Jul 1. Bioorg Med Chem Lett. 2010. PMID: 20655216

6

Predicting in vivo safety characteristics using physiochemical properties and in vitro assays.

Greene N, Song M. Greene N, et al. Future Med Chem. 2011 Sep;3(12):1503-11. doi: 10.4155/fmc.11.89. Future Med Chem. 2011. PMID: 21882943

7

Analysis of Pfizer compounds in EPA's ToxCast chemicals-assay space.

Shah F, Greene N. Shah F, et al. Among authors: greene n. Chem Res Toxicol. 2014 Jan 21;27(1):86-98. doi: 10.1021/tx400343t. Epub 2013 Dec 11. Chem Res Toxicol. 2014. PMID: 24328225

8

(Q)SAR: A Tool for the Toxicologist.

Steinbach T, Gad-McDonald S, Kruhlak N, Powley M, Greene N. Steinbach T, et al. Among authors: greene n. Int J Toxicol. 2015 Jul-Aug;34(4):352-4. doi: 10.1177/1091581815584914. Epub 2015 May 15. Int J Toxicol. 2015. PMID: 25979517

9

Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanistic in vitro Assays.

Shah F, Leung L, Barton HA, Will Y, Rodrigues AD, Greene N, Aleo MD. Shah F, et al. Among authors: greene n. Toxicol Sci. 2015 Oct;147(2):500-14. doi: 10.1093/toxsci/kfv152. Epub 2015 Jul 23. Toxicol Sci. 2015. PMID: 26206150

10

The application of structure-based assessment to support safety and chemistry diligence to manage genotoxic impurities in active pharmaceutical ingredients during drug development.

Dobo KL, Greene N, Cyr MO, Caron S, Ku WW. Dobo KL, et al. Among authors: greene n. Regul Toxicol Pharmacol. 2006 Apr;44(3):282-93. doi: 10.1016/j.yrtph.2006.01.004. Epub 2006 Feb 7. Regul Toxicol Pharmacol. 2006. PMID: 16464524

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