Fernandez-Capetillo O - Search Results

1

p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint.

Lafarga V, Cuadrado A, Lopez de Silanes I, Bengoechea R, Fernandez-Capetillo O, Nebreda AR. Lafarga V, et al. Mol Cell Biol. 2009 Aug;29(16):4341-51. doi: 10.1128/MCB.00210-09. Epub 2009 Jun 15. Mol Cell Biol. 2009. PMID: 19528229 Free PMC article.

2

ATM regulates ATR chromatin loading in response to DNA double-strand breaks.

Cuadrado M, Martinez-Pastor B, Murga M, Toledo LI, Gutierrez-Martinez P, Lopez E, Fernandez-Capetillo O. Cuadrado M, et al. J Exp Med. 2006 Feb 20;203(2):297-303. doi: 10.1084/jem.20051923. Epub 2006 Feb 6. J Exp Med. 2006. PMID: 16461339 Free PMC article.

3

ATR signaling can drive cells into senescence in the absence of DNA breaks.

Toledo LI, Murga M, Gutierrez-Martinez P, Soria R, Fernandez-Capetillo O. Toledo LI, et al. Genes Dev. 2008 Feb 1;22(3):297-302. doi: 10.1101/gad.452308. Genes Dev. 2008. PMID: 18245444 Free PMC article.

4

ATM breaks into heterochromatin.

Fernandez-Capetillo O, Nussenzweig A. Fernandez-Capetillo O, et al. Mol Cell. 2008 Aug 8;31(3):303-4. doi: 10.1016/j.molcel.2008.07.004. Mol Cell. 2008. PMID: 18691960 Free article.

5

Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.

Efeyan A, Murga M, Martinez-Pastor B, Ortega-Molina A, Soria R, Collado M, Fernandez-Capetillo O, Serrano M. Efeyan A, et al. PLoS One. 2009;4(5):e5475. doi: 10.1371/journal.pone.0005475. Epub 2009 May 7. PLoS One. 2009. PMID: 19421407 Free PMC article.

6

A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging.

Murga M, Bunting S, Montaña MF, Soria R, Mulero F, Cañamero M, Lee Y, McKinnon PJ, Nussenzweig A, Fernandez-Capetillo O. Murga M, et al. Nat Genet. 2009 Aug;41(8):891-8. doi: 10.1038/ng.420. Epub 2009 Jul 20. Nat Genet. 2009. PMID: 19620979 Free PMC article.

7

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.

Martínez P, Thanasoula M, Muñoz P, Liao C, Tejera A, McNees C, Flores JM, Fernández-Capetillo O, Tarsounas M, Blasco MA. Martínez P, et al. Genes Dev. 2009 Sep 1;23(17):2060-75. doi: 10.1101/gad.543509. Epub 2009 Aug 13. Genes Dev. 2009. PMID: 19679647 Free PMC article.

8

p27Kip1 stabilization is essential for the maintenance of cell cycle arrest in response to DNA damage.

Cuadrado M, Gutierrez-Martinez P, Swat A, Nebreda AR, Fernandez-Capetillo O. Cuadrado M, et al. Cancer Res. 2009 Nov 15;69(22):8726-32. doi: 10.1158/0008-5472.CAN-09-0729. Epub 2009 Oct 20. Cancer Res. 2009. PMID: 19843869 Free PMC article.

9

Overall Cdk activity modulates the DNA damage response in mammalian cells.

Cerqueira A, Santamaría D, Martínez-Pastor B, Cuadrado M, Fernández-Capetillo O, Barbacid M. Cerqueira A, et al. J Cell Biol. 2009 Dec 14;187(6):773-80. doi: 10.1083/jcb.200903033. J Cell Biol. 2009. PMID: 19995934 Free PMC article.

10

ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase.

McNees CJ, Tejera AM, Martínez P, Murga M, Mulero F, Fernandez-Capetillo O, Blasco MA. McNees CJ, et al. J Cell Biol. 2010 Mar 8;188(5):639-52. doi: 10.1083/jcb.200908136. J Cell Biol. 2010. PMID: 20212315 Free PMC article.

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