Akinaga S - Search Results

1

Engineered therapeutic antibodies with improved effector functions.

Kubota T, Niwa R, Satoh M, Akinaga S, Shitara K, Hanai N. Kubota T, et al. Among authors: akinaga s. Cancer Sci. 2009 Sep;100(9):1566-72. doi: 10.1111/j.1349-7006.2009.01222.x. Epub 2009 May 18. Cancer Sci. 2009. PMID: 19538497 Free PMC article. Review.

2

Therapeutic potential of chimeric anti-(ganglioside GD3) antibody KM871: antitumor activity in xenograft model of melanoma and effector function analysis.

Kanazawa J, Ohta S, Shitara K, Fujita F, Fujita M, Hanai N, Akinaga S, Okabe M. Kanazawa J, et al. Among authors: akinaga s. Cancer Immunol Immunother. 2000 Jul;49(4-5):253-8. doi: 10.1007/s002620000101. Cancer Immunol Immunother. 2000. PMID: 10941908 Free PMC article.

3

A neutralizing anti-fibroblast growth factor 8 monoclonal antibody shows potent antitumor activity against androgen-dependent mouse mammary tumors in vivo.

Shimada N, Ishii T, Imada T, Takaba K, Sasaki Y, Maruyama-Takahashi K, Maekawa-Tokuda Y, Kusaka H, Akinaga S, Tanaka A, Shitara K. Shimada N, et al. Among authors: akinaga s. Clin Cancer Res. 2005 May 15;11(10):3897-904. doi: 10.1158/1078-0432.CCR-04-2358. Clin Cancer Res. 2005. PMID: 15897591

4

Defucosylated humanized anti-CCR4 monoclonal antibody KW-0761 as a novel immunotherapeutic agent for adult T-cell leukemia/lymphoma.

Ishii T, Ishida T, Utsunomiya A, Inagaki A, Yano H, Komatsu H, Iida S, Imada K, Uchiyama T, Akinaga S, Shitara K, Ueda R. Ishii T, et al. Among authors: akinaga s. Clin Cancer Res. 2010 Mar 1;16(5):1520-31. doi: 10.1158/1078-0432.CCR-09-2697. Epub 2010 Feb 16. Clin Cancer Res. 2010. PMID: 20160057

5

A neutralizing anti-fibroblast growth factor (FGF) 8 monoclonal antibody shows anti-tumor activity against FGF8b-expressing LNCaP xenografts in androgen-dependent and -independent conditions.

Maruyama-Takahashi K, Shimada N, Imada T, Maekawa-Tokuda Y, Ishii T, Ouchi J, Kusaka H, Miyaji H, Akinaga S, Tanaka A, Shitara K. Maruyama-Takahashi K, et al. Among authors: akinaga s. Prostate. 2008 May 1;68(6):640-50. doi: 10.1002/pros.20728. Prostate. 2008. PMID: 18213631

6

The CC chemokine receptor 4 as a novel specific molecular target for immunotherapy in adult T-Cell leukemia/lymphoma.

Ishida T, Iida S, Akatsuka Y, Ishii T, Miyazaki M, Komatsu H, Inagaki H, Okada N, Fujita T, Shitara K, Akinaga S, Takahashi T, Utsunomiya A, Ueda R. Ishida T, et al. Among authors: akinaga s. Clin Cancer Res. 2004 Nov 15;10(22):7529-39. doi: 10.1158/1078-0432.CCR-04-0983. Clin Cancer Res. 2004. PMID: 15569983

7

UCN-01 (7-hydoxystaurosporine) inhibits in vivo growth of human cancer cells through selective perturbation of G1 phase checkpoint machinery.

Abe S, Kubota T, Otani Y, Furukawa T, Watanabe M, Kumai K, Akiyama T, Akinaga S, Kitajima M. Abe S, et al. Among authors: akinaga s. Jpn J Cancer Res. 2001 May;92(5):537-45. doi: 10.1111/j.1349-7006.2001.tb01127.x. Jpn J Cancer Res. 2001. PMID: 11376563 Free PMC article.

8

Preclinical and first-in-human phase I studies of KW-2450, an oral tyrosine kinase inhibitor with insulin-like growth factor receptor-1/insulin receptor selectivity.

Schwartz GK, Dickson MA, LoRusso PM, Sausville EA, Maekawa Y, Watanabe Y, Kashima N, Nakashima D, Akinaga S. Schwartz GK, et al. Among authors: akinaga s. Cancer Sci. 2016 Apr;107(4):499-506. doi: 10.1111/cas.12906. Epub 2016 Mar 28. Cancer Sci. 2016. PMID: 26850678 Free PMC article. Clinical Trial.

9

Genetically engineered humanized anti-ganglioside GM2 antibody against multiple organ metastasis produced by GM2-expressing small-cell lung cancer cells.

Yamada T, Bando H, Takeuchi S, Kita K, Li Q, Wang W, Akinaga S, Nishioka Y, Sone S, Yano S. Yamada T, et al. Among authors: akinaga s. Cancer Sci. 2011 Dec;102(12):2157-63. doi: 10.1111/j.1349-7006.2011.02093.x. Epub 2011 Sep 30. Cancer Sci. 2011. PMID: 21895875 Free article.

10

Phase I study of highly selective inhibitor of VEGFR tyrosine kinase, tivozanib, in Japanese patients with solid tumors.

Niwakawa M, Yamaguchi R, Onozawa Y, Yasui H, Taku K, Naito T, Akinaga S, Boku N, Yamamoto N. Niwakawa M, et al. Among authors: akinaga s. Cancer Sci. 2013 Aug;104(8):1039-44. doi: 10.1111/cas.12197. Epub 2013 Jun 21. Cancer Sci. 2013. PMID: 23679664 Free PMC article. Clinical Trial.

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