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Multiple pathways guide oxygen diffusion into flavoenzyme active sites.
Baron R, Riley C, Chenprakhon P, Thotsaporn K, Winter RT, Alfieri A, Forneris F, van Berkel WJ, Chaiyen P, Fraaije MW, Mattevi A, McCammon JA. Baron R, et al. Among authors: chenprakhon p. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10603-8. doi: 10.1073/pnas.0903809106. Epub 2009 Jun 16. Proc Natl Acad Sci U S A. 2009. PMID: 19541622 Free PMC article.
Tuning of pKa values activates substrates in flavin-dependent aromatic hydroxylases.
Pitsawong W, Chenprakhon P, Dhammaraj T, Medhanavyn D, Sucharitakul J, Tongsook C, van Berkel WJH, Chaiyen P, Miller AF. Pitsawong W, et al. Among authors: chenprakhon p. J Biol Chem. 2020 Mar 20;295(12):3965-3981. doi: 10.1074/jbc.RA119.011884. Epub 2020 Feb 2. J Biol Chem. 2020. PMID: 32014994 Free PMC article.
Phenolic hydroxylases.
Chenprakhon P, Pimviriyakul P, Tongsook C, Chaiyen P. Chenprakhon P, et al. Enzymes. 2020;47:283-326. doi: 10.1016/bs.enz.2020.05.008. Epub 2020 Jul 18. Enzymes. 2020. PMID: 32951826
Dissecting the low catalytic capability of flavin-dependent halogenases.
Phintha A, Prakinee K, Jaruwat A, Lawan N, Visitsatthawong S, Kantiwiriyawanitch C, Songsungthong W, Trisrivirat D, Chenprakhon P, Mulholland A, van Pée KH, Chitnumsub P, Chaiyen P. Phintha A, et al. Among authors: chenprakhon p. J Biol Chem. 2021 Jan-Jun;296:100068. doi: 10.1074/jbc.RA120.016004. Epub 2020 Nov 23. J Biol Chem. 2021. PMID: 33465708 Free PMC article.
13 results