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Complement factor h is critical in the maintenance of retinal perfusion.
Lundh von Leithner P, Kam JH, Bainbridge J, Catchpole I, Gough G, Coffey P, Jeffery G. Lundh von Leithner P, et al. Among authors: coffey p. Am J Pathol. 2009 Jul;175(1):412-21. doi: 10.2353/ajpath.2009.080927. Epub 2009 Jun 18. Am J Pathol. 2009. PMID: 19541934 Free PMC article.
Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model.
Catchpole I, Germaschewski V, Hoh Kam J, Lundh von Leithner P, Ford S, Gough G, Adamson P, Overend P, Hilpert J, López FJ, Ng YS, Coffey P, Jeffery G. Catchpole I, et al. Among authors: coffey p. PLoS One. 2013 Jun 14;8(6):e65518. doi: 10.1371/journal.pone.0065518. Print 2013. PLoS One. 2013. PMID: 23799019 Free PMC article.
Hsp90 inhibition protects against inherited retinal degeneration.
Aguilà M, Bevilacqua D, McCulley C, Schwarz N, Athanasiou D, Kanuga N, Novoselov SS, Lange CA, Ali RR, Bainbridge JW, Gias C, Coffey PJ, Garriga P, Cheetham ME. Aguilà M, et al. Among authors: coffey pj. Hum Mol Genet. 2014 Apr 15;23(8):2164-75. doi: 10.1093/hmg/ddt613. Epub 2013 Dec 2. Hum Mol Genet. 2014. PMID: 24301679 Free PMC article.
Investigation of PTC124-mediated translational readthrough in a retinal organoid model of AIPL1-associated Leber congenital amaurosis.
Leung A, Sacristan-Reviriego A, Perdigão PRL, Sai H, Georgiou M, Kalitzeos A, Carr AF, Coffey PJ, Michaelides M, Bainbridge J, Cheetham ME, van der Spuy J. Leung A, et al. Stem Cell Reports. 2022 Oct 11;17(10):2187-2202. doi: 10.1016/j.stemcr.2022.08.005. Epub 2022 Sep 8. Stem Cell Reports. 2022. PMID: 36084639 Free PMC article.
258 results