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FcRn binding is not sufficient for achieving systemic therapeutic levels of immunoglobulin G after oral delivery of enteric-coated capsules in cynomolgus macaques.
Muzammil S, Mabus JR, Cooper PR, Brezski RJ, Bement CB, Perkinson R, Huebert ND, Thompson S, Levine D, Kliwinski C, Bradley D, Hornby PJ. Muzammil S, et al. Among authors: hornby pj. Pharmacol Res Perspect. 2016 Apr 25;4(3):e00218. doi: 10.1002/prp2.218. eCollection 2016 Jun. Pharmacol Res Perspect. 2016. PMID: 27433338 Free PMC article.
Contribution of FcRn binding to intestinal uptake of IgG in suckling rat pups and human FcRn-transgenic mice.
Kliwinski C, Cooper PR, Perkinson R, Mabus JR, Tam SH, Wilkinson TM, Giles-Komar J, Scallon B, Powers GD, Hornby PJ. Kliwinski C, et al. Among authors: hornby pj. Am J Physiol Gastrointest Liver Physiol. 2013 Feb 1;304(3):G262-70. doi: 10.1152/ajpgi.00340.2012. Epub 2012 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23220220 Free article.
98 results