Wrishko RE - Search Results

1

Population pharmacokinetic analyses to evaluate the influence of intrinsic and extrinsic factors on exposure of prasugrel active metabolite in TRITON-TIMI 38.

Wrishko RE, Ernest CS 2nd, Small DS, Li YG, Weerakkody GJ, Riesmeyer JR, Macias WL, Rohatagi S, Salazar DE, Antman EM, Wiviott SD, Braunwald E, Ni L. Wrishko RE, et al. J Clin Pharmacol. 2009 Aug;49(8):984-98. doi: 10.1177/0091270009337942. Epub 2009 Jun 22. J Clin Pharmacol. 2009. PMID: 19546250

2

Tadalafil pharmacokinetics in healthy subjects.

Forgue ST, Patterson BE, Bedding AW, Payne CD, Phillips DL, Wrishko RE, Mitchell MI. Forgue ST, et al. Among authors: wrishko re. Br J Clin Pharmacol. 2006 Mar;61(3):280-8. doi: 10.1111/j.1365-2125.2005.02553.x. Br J Clin Pharmacol. 2006. PMID: 16487221 Free PMC article.

3

Effects of gender, age, diabetes mellitus and renal and hepatic impairment on tadalafil pharmacokinetics.

Forgue ST, Phillips DL, Bedding AW, Payne CD, Jewell H, Patterson BE, Wrishko RE, Mitchell MI. Forgue ST, et al. Among authors: wrishko re. Br J Clin Pharmacol. 2007 Jan;63(1):24-35. doi: 10.1111/j.1365-2125.2006.02726.x. Epub 2006 Jul 21. Br J Clin Pharmacol. 2007. PMID: 16869816 Free PMC article.

4

Pharmacokinetic interaction between tadalafil and bosentan in healthy male subjects.

Wrishko RE, Dingemanse J, Yu A, Darstein C, Phillips DL, Mitchell MI. Wrishko RE, et al. J Clin Pharmacol. 2008 May;48(5):610-8. doi: 10.1177/0091270008315315. Epub 2008 Feb 27. J Clin Pharmacol. 2008. PMID: 18305126 Clinical Trial.

5

Population pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in aspirin-treated patients with stable coronary artery disease.

Ernest CS 2nd, Small DS, Rohatagi S, Salazar DE, Wallentin L, Winters KJ, Wrishko RE. Ernest CS 2nd, et al. Among authors: wrishko re. J Pharmacokinet Pharmacodyn. 2008 Dec;35(6):593-618. doi: 10.1007/s10928-008-9103-7. Epub 2008 Nov 21. J Pharmacokinet Pharmacodyn. 2008. PMID: 19023649 Clinical Trial.

6

Prediction of prasugrel active metabolite concentrations from 2 downstream inactive metabolite concentrations using multilinear regression analysis.

Ernest CS 2nd, Heathman MA, Wrishko RE. Ernest CS 2nd, et al. Among authors: wrishko re. J Clin Pharmacol. 2009 Aug;49(8):973-83. doi: 10.1177/0091270009340416. J Clin Pharmacol. 2009. PMID: 19602721

7

Effect of age on the pharmacokinetics and pharmacodynamics of prasugrel during multiple dosing: an open-label, single-sequence, clinical trial.

Small DS, Wrishko RE, Ernest CS 2nd, Ni L, Winters KJ, Farid NA, Li YG, Salazar DE, Payne CD. Small DS, et al. Among authors: wrishko re. Drugs Aging. 2009;26(9):781-90. doi: 10.2165/11315780-000000000-00000. Drugs Aging. 2009. PMID: 19728751 Clinical Trial.

8

Prasugrel pharmacokinetics and pharmacodynamics in subjects with moderate renal impairment and end-stage renal disease.

Small DS, Wrishko RE, Ernest CS 2nd, Ni L, Winters KJ, Farid NA, Li YG, Brandt JT, Salazar DE, Borel AG, Kles KA, Payne CD. Small DS, et al. Among authors: wrishko re. J Clin Pharm Ther. 2009 Oct;34(5):585-94. doi: 10.1111/j.1365-2710.2009.01068.x. J Clin Pharm Ther. 2009. PMID: 19744014

9

Relationship between exposure to prasugrel active metabolite and clinical outcomes in the TRITON-TIMI 38 substudy.

Riesmeyer JS, Salazar DE, Weerakkody GJ, Ni L, Wrishko RE, Ernest CS 2nd, Luo J, Li YG, Small DS, Rohatagi S, Macias WL. Riesmeyer JS, et al. Among authors: wrishko re. J Clin Pharmacol. 2012 Jun;52(6):789-97. doi: 10.1177/0091270011406280. Epub 2011 May 31. J Clin Pharmacol. 2012. PMID: 21628601 Clinical Trial.

10

Safety, efficacy, and pharmacokinetic overview of low-dose daily administration of tadalafil.

Wrishko R, Sorsaburu S, Wong D, Strawbridge A, McGill J. Wrishko R, et al. J Sex Med. 2009 Jul;6(7):2039-48. doi: 10.1111/j.1743-6109.2009.01301.x. Epub 2009 Apr 28. J Sex Med. 2009. PMID: 19453893 Clinical Trial.

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