Cornwell PD - Search Results

1

Qualification of cardiac troponin I concentration in mouse serum using isoproterenol and implementation in pharmacology studies to accelerate drug development.

Engle SK, Jordan WH, Pritt ML, Chiang AY, Davis MA, Zimmermann JL, Rudmann DG, Heinz-Taheny KM, Irizarry AR, Yamamoto Y, Mendel D, Schultze AE, Cornwell PD, Watson DE. Engle SK, et al. Among authors: cornwell pd. Toxicol Pathol. 2009 Aug;37(5):617-28. doi: 10.1177/0192623309339502. Epub 2009 Jun 23. Toxicol Pathol. 2009. PMID: 19549929

2

Pancreatic Effects of a Bruton's Tyrosine Kinase Small-molecule Inhibitor in Rats Are Strain-dependent.

Bhaskaran M, Cornwell PD, Sorden SD, Elwell MR, Russell NR, Pritt ML, Vahle JL. Bhaskaran M, et al. Among authors: cornwell pd. Toxicol Pathol. 2018 Jun;46(4):460-472. doi: 10.1177/0192623318770163. Epub 2018 Apr 26. Toxicol Pathol. 2018. PMID: 29699458

3

Investigating the mechanistic basis for hepatic toxicity induced by an experimental chemokine receptor 5 (CCR5) antagonist using a compendium of gene expression profiles.

Cornwell PD, Ulrich RG. Cornwell PD, et al. Toxicol Pathol. 2007 Jun;35(4):576-88. doi: 10.1080/01926230701383194. Toxicol Pathol. 2007. PMID: 17654398

4

Drug Development 101: A Primer.

Buckley LA, Bebenek I, Cornwell PD, Hodowanec A, Jensen EC, Murphy C, Ghantous HN. Buckley LA, et al. Among authors: cornwell pd. Int J Toxicol. 2020 Sep/Oct;39(5):379-396. doi: 10.1177/1091581820939083. Epub 2020 Aug 7. Int J Toxicol. 2020. PMID: 32762387

5

LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth.

Liu L, Zeng W, Wortinger MA, Yan SB, Cornwell P, Peek VL, Stephens JR, Tetreault JW, Xia J, Manro JR, Credille KM, Ballard DW, Brown-Augsburger P, Wacheck V, Chow CK, Huang L, Wang Y, Denning I, Davies J, Tang Y, Vaillancourt P, Lu J. Liu L, et al. Clin Cancer Res. 2014 Dec 1;20(23):6059-70. doi: 10.1158/1078-0432.CCR-14-0543. Epub 2014 Sep 17. Clin Cancer Res. 2014. PMID: 25231402

6

Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo.

Slatter JG, Cheng O, Cornwell PD, de Souza A, Rockett J, Rushmore T, Hartley D, Evers R, He Y, Dai X, Hu R, Caguyong M, Roberts CJ, Castle J, Ulrich RG. Slatter JG, et al. Among authors: cornwell pd. Xenobiotica. 2006 Oct-Nov;36(10-11):902-37. doi: 10.1080/00498250600861694. Xenobiotica. 2006. PMID: 17118914

7

Profiling of hepatic gene expression in rats treated with fibric acid analogs.

Cornwell PD, De Souza AT, Ulrich RG. Cornwell PD, et al. Mutat Res. 2004 May 18;549(1-2):131-45. doi: 10.1016/j.mrfmmm.2003.12.019. Mutat Res. 2004. PMID: 15120967

8

Agonists of the peroxisome proliferator-activated receptor alpha induce a fiber-type-selective transcriptional response in rat skeletal muscle.

De Souza AT, Cornwell PD, Dai X, Caguyong MJ, Ulrich RG. De Souza AT, et al. Among authors: cornwell pd. Toxicol Sci. 2006 Aug;92(2):578-86. doi: 10.1093/toxsci/kfl019. Epub 2006 May 17. Toxicol Sci. 2006. PMID: 16707586

9

Gene expression profiling in spleens of deoxynivalenol-exposed mice: immediate early genes as primary targets.

Kinser S, Jia Q, Li M, Laughter A, Cornwell P, Corton JC, Pestka J. Kinser S, et al. J Toxicol Environ Health A. 2004 Sep 24;67(18):1423-41. doi: 10.1080/15287390490483827. J Toxicol Environ Health A. 2004. PMID: 15371230

10

Estimation of acceptable daily intake values based on modeling and in vivo mutagenicity of NDSRIs of fluoxetine, duloxetine and atomoxetine.

Jolly RA, Cornwell PD, Noteboom J, Sayyed FB, Thapa B, Buckley LA. Jolly RA, et al. Among authors: cornwell pd. Regul Toxicol Pharmacol. 2024 Sep;152:105672. doi: 10.1016/j.yrtph.2024.105672. Epub 2024 Jul 4. Regul Toxicol Pharmacol. 2024. PMID: 38968965

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