Majors BS - Search Results

1

Mcl-1 overexpression leads to higher viabilities and increased production of humanized monoclonal antibody in Chinese hamster ovary cells.

Majors BS, Betenbaugh MJ, Pederson NE, Chiang GG. Majors BS, et al. Biotechnol Prog. 2009 Jul-Aug;25(4):1161-8. doi: 10.1002/btpr.192. Biotechnol Prog. 2009. PMID: 19551877

2

Inhibiting the apoptosis pathway using MDM2 in mammalian cell cultures.

Arden N, Majors BS, Ahn SH, Oyler G, Betenbaugh MJ. Arden N, et al. Among authors: majors bs. Biotechnol Bioeng. 2007 Jun 15;97(3):601-14. doi: 10.1002/bit.21254. Biotechnol Bioeng. 2007. PMID: 17149774

3

Links between metabolism and apoptosis in mammalian cells: applications for anti-apoptosis engineering.

Majors BS, Betenbaugh MJ, Chiang GG. Majors BS, et al. Metab Eng. 2007 Jul;9(4):317-26. doi: 10.1016/j.ymben.2007.05.003. Epub 2007 May 23. Metab Eng. 2007. PMID: 17611135 Review.

4

Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-x(L).

Majors BS, Betenbaugh MJ, Pederson NE, Chiang GG. Majors BS, et al. Biotechnol Bioeng. 2008 Oct 15;101(3):567-78. doi: 10.1002/bit.21917. Biotechnol Bioeng. 2008. PMID: 18727128

5

E2F-1 overexpression increases viable cell density in batch cultures of Chinese hamster ovary cells.

Majors BS, Arden N, Oyler GA, Chiang GG, Pederson NE, Betenbaugh MJ. Majors BS, et al. J Biotechnol. 2008 Nov 25;138(3-4):103-6. doi: 10.1016/j.jbiotec.2008.08.003. Epub 2008 Aug 20. J Biotechnol. 2008. PMID: 18778741

6

Protein and genome evolution in Mammalian cells for biotechnology applications.

Majors BS, Chiang GG, Betenbaugh MJ. Majors BS, et al. Mol Biotechnol. 2009 Jun;42(2):216-23. doi: 10.1007/s12033-009-9156-x. Epub 2009 Apr 15. Mol Biotechnol. 2009. PMID: 19367473 Review.

7

Increased expression of the integral membrane protein ErbB2 in Chinese hamster ovary cells expressing the anti-apoptotic gene Bcl-xL.

O'Connor S, Li E, Majors BS, He L, Placone J, Baycin D, Betenbaugh MJ, Hristova K. O'Connor S, et al. Among authors: majors bs. Protein Expr Purif. 2009 Sep;67(1):41-7. doi: 10.1016/j.pep.2009.04.007. Epub 2009 Apr 17. Protein Expr Purif. 2009. PMID: 19376231 Free PMC article.

8

Directed evolution of mammalian anti-apoptosis proteins by somatic hypermutation.

Majors BS, Chiang GG, Pederson NE, Betenbaugh MJ. Majors BS, et al. Protein Eng Des Sel. 2012 Jan;25(1):27-38. doi: 10.1093/protein/gzr052. Epub 2011 Dec 9. Protein Eng Des Sel. 2012. PMID: 22160868 Free PMC article.

9

A novel microRNA mmu-miR-466h affects apoptosis regulation in mammalian cells.

Druz A, Chu C, Majors B, Santuary R, Betenbaugh M, Shiloach J. Druz A, et al. Biotechnol Bioeng. 2011 Jul;108(7):1651-61. doi: 10.1002/bit.23092. Epub 2011 Mar 11. Biotechnol Bioeng. 2011. PMID: 21337326 Free PMC article.

10

Structure-function relationships of gene delivery vectors in a limited polycation library.

Chen DJ, Majors BS, Zelikin A, Putnam D. Chen DJ, et al. Among authors: majors bs. J Control Release. 2005 Mar 2;103(1):273-83. doi: 10.1016/j.jconrel.2004.11.028. J Control Release. 2005. PMID: 15710517

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