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Potent, orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors.
Koltun DO, Zilbershtein TM, Migulin VA, Vasilevich NI, Parkhill EQ, Glushkov AI, McGregor MJ, Brunn SA, Chu N, Hao J, Mollova N, Leung K, Chisholm JW, Zablocki J. Koltun DO, et al. Among authors: vasilevich ni. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4070-4. doi: 10.1016/j.bmcl.2009.06.017. Epub 2009 Jun 13. Bioorg Med Chem Lett. 2009. PMID: 19577469
Novel, potent, selective, and metabolically stable stearoyl-CoA desaturase (SCD) inhibitors.
Koltun DO, Parkhill EQ, Vasilevich NI, Glushkov AI, Zilbershtein TM, Ivanov AV, Cole AG, Henderson I, Zautke NA, Brunn SA, Mollova N, Leung K, Chisholm JW, Zablocki J. Koltun DO, et al. Among authors: vasilevich ni. Bioorg Med Chem Lett. 2009 Apr 1;19(7):2048-52. doi: 10.1016/j.bmcl.2009.02.019. Epub 2009 Feb 8. Bioorg Med Chem Lett. 2009. PMID: 19249203
Orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors.
Koltun DO, Vasilevich NI, Parkhill EQ, Glushkov AI, Zilbershtein TM, Mayboroda EI, Boze MA, Cole AG, Henderson I, Zautke NA, Brunn SA, Chu N, Hao J, Mollova N, Leung K, Chisholm JW, Zablocki J. Koltun DO, et al. Among authors: vasilevich ni. Bioorg Med Chem Lett. 2009 Jun 1;19(11):3050-3. doi: 10.1016/j.bmcl.2009.04.004. Epub 2009 Apr 8. Bioorg Med Chem Lett. 2009. PMID: 19394219
Oxygen-containing fragments in natural products.
Titarenko Z, Vasilevich N, Zernov V, Kirpichenok M, Genis D. Titarenko Z, et al. J Comput Aided Mol Des. 2013 Feb;27(2):125-60. doi: 10.1007/s10822-012-9629-z. Epub 2012 Dec 28. J Comput Aided Mol Des. 2013. PMID: 23271273
17 results