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The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism.
Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, MacDonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R. Sebastián C, et al. Among authors: zwaans bm. Cell. 2012 Dec 7;151(6):1185-99. doi: 10.1016/j.cell.2012.10.047. Cell. 2012. PMID: 23217706 Free PMC article.
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y. Park J, et al. Among authors: zwaans bm. Mol Cell. 2013 Jun 27;50(6):919-30. doi: 10.1016/j.molcel.2013.06.001. Mol Cell. 2013. PMID: 23806337 Free PMC article.
SIRT3: as simple as it seems?
Lombard DB, Zwaans BM. Lombard DB, et al. Among authors: zwaans bm. Gerontology. 2014;60(1):56-64. doi: 10.1159/000354382. Epub 2013 Oct 25. Gerontology. 2014. PMID: 24192814 Free PMC article. Review.
The first identification of lysine malonylation substrates and its regulatory enzyme.
Peng C, Lu Z, Xie Z, Cheng Z, Chen Y, Tan M, Luo H, Zhang Y, He W, Yang K, Zwaans BM, Tishkoff D, Ho L, Lombard D, He TC, Dai J, Verdin E, Ye Y, Zhao Y. Peng C, et al. Among authors: zwaans bm. Mol Cell Proteomics. 2011 Dec;10(12):M111.012658. doi: 10.1074/mcp.M111.012658. Epub 2011 Sep 9. Mol Cell Proteomics. 2011. PMID: 21908771 Free PMC article.
Calcification of multipotent prostate tumor endothelium.
Dudley AC, Khan ZA, Shih SC, Kang SY, Zwaans BM, Bischoff J, Klagsbrun M. Dudley AC, et al. Among authors: zwaans bm. Cancer Cell. 2008 Sep 9;14(3):201-11. doi: 10.1016/j.ccr.2008.06.017. Cancer Cell. 2008. PMID: 18772110 Free PMC article.
Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas.
Shahrabi-Farahani S, Wang L, Zwaans BM, Santana JM, Shimizu A, Takashima S, Kreuter M, Coultas L, D'Amore PA, Arbeit JM, Akslen LA, Bielenberg DR. Shahrabi-Farahani S, et al. Among authors: zwaans bm. Lab Invest. 2014 Jul;94(7):752-65. doi: 10.1038/labinvest.2014.66. Epub 2014 May 5. Lab Invest. 2014. PMID: 24791743 Free PMC article.
Increased smooth muscle contractility in mice deficient for neuropilin 2.
Bielenberg DR, Seth A, Shimizu A, Pelton K, Cristofaro V, Ramachandran A, Zwaans BM, Chen C, Krishnan R, Seth M, Huang L, Takashima S, Klagsbrun M, Sullivan MP, Adam RM. Bielenberg DR, et al. Among authors: zwaans bm. Am J Pathol. 2012 Aug;181(2):548-59. doi: 10.1016/j.ajpath.2012.04.013. Epub 2012 Jun 9. Am J Pathol. 2012. PMID: 22688055 Free PMC article.
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